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静脉内给予非离子型低渗造影剂行冠状动脉造影后出现迟发、不常见的非心源性肺水肿。

A delayed, unusual non-cardiogenic pulmonary edema after intravascular administration of non-ionic, low osmolar radiocontrast media for coronary angiography.

机构信息

Division of Cardiology, Department of Medicine, Seoul Paik Hospital, Inje University School of Medicine, Seoul, Korea.

出版信息

Korean Circ J. 2013 Jul;43(7):500-3. doi: 10.4070/kcj.2013.43.7.500. Epub 2013 Jul 31.

DOI:10.4070/kcj.2013.43.7.500
PMID:23964299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3744740/
Abstract

Non-cardiogenic pulmonary edema (NCPE) is a rare adverse reaction to iodinated radiocontrast media (RCM), in which all previous cases were immediate reactions. A 56-year-old male was given iopamidol, a non-ionic, low osmolar RCM, during coronary artery angiography. He developed pulmonary edema and fever a day after the procedure. Despite diuretic therapy, the patient's pulmonary edema worsened and his high fever persisted. The patient's pulmonary edema was eventually resolved with intravenous steroid treatment. We interpreted the patient's condition as NCPE manifesting as a delayed reaction to RCM. To our knowledge, our case is the first to show NCPE as a delayed hypersensitivity reaction.

摘要

非心源性肺水肿（NCPE）是碘造影剂（RCM）罕见的不良反应，此前所有病例均为即刻反应。一名 56 岁男性在冠状动脉造影期间使用了一种非离子型、低渗的 RCM 碘帕醇。在操作后一天，他出现肺水肿和发热。尽管给予利尿剂治疗，但患者的肺水肿仍恶化，高热持续。患者的肺水肿最终通过静脉注射类固醇治疗得到缓解。我们将患者的病情解释为 RCM 迟发性过敏反应引起的 NCPE。据我们所知，我们的病例是首例显示 NCPE 为迟发性过敏反应的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/0f90addec153/kcj-43-500-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/39a8827f514f/kcj-43-500-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/0df756ff36fc/kcj-43-500-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/0f90addec153/kcj-43-500-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/39a8827f514f/kcj-43-500-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/0df756ff36fc/kcj-43-500-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a9/3744740/0f90addec153/kcj-43-500-g003.jpg

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本文引用的文献

1
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Eur Radiol. 2011 Nov;21(11):2305-10. doi: 10.1007/s00330-011-2200-9. Epub 2011 Jul 16.
2
Anaphylactoid reactions to radiocontrast agents: prevention and treatment in the cardiac catheterization laboratory.造影剂类过敏反应：心脏导管室中的预防与治疗
J Invasive Cardiol. 2009 Oct;21(10):548-51.
3
Immediate and delayed reactions to radiocontrast media: is there an allergic mechanism?放射性造影剂的即刻和延迟反应：是否存在过敏机制？
Open Access Emerg Med. 2018 Jun 14;10:75-79. doi: 10.2147/OAEM.S154081. eCollection 2018.
4
Non-cardiogenic acute pulmonary edema in elderly patient with Dressler syndrome associated pulmonary embolism.老年患者患德雷斯勒综合征合并肺栓塞时的非心源性急性肺水肿
J Geriatr Cardiol. 2016 Dec;13(12):998-1001. doi: 10.11909/j.issn.1671-5411.2016.12.009.
Immunol Allergy Clin North Am. 2009 Aug;29(3):453-68. doi: 10.1016/j.iac.2009.04.001.
4
Adverse reactions to intravenous iodinated contrast media: a primer for radiologists.静脉注射碘造影剂的不良反应：放射科医生入门指南
Emerg Radiol. 2006 Jul;12(5):210-5. doi: 10.1007/s10140-006-0488-6. Epub 2006 May 11.
5
[Non-cardiogenic pulmonary edema induced by non-ionic radiographic contrast media during the coil embolization for a ruptured cerebral aneurysm].[脑动脉瘤破裂弹簧圈栓塞术中非离子型造影剂诱发非心源性肺水肿]
No Shinkei Geka. 2005 Jul;33(7):703-7.
6
Management of hypersensitivity reactions to iodinated contrast media.碘化造影剂过敏反应的管理。
Allergy. 2005 Feb;60(2):150-8. doi: 10.1111/j.1398-9995.2005.00745.x.
7
Late adverse reactions to intravascular iodinated contrast media.血管内碘化造影剂的迟发不良反应。
Eur Radiol. 2003 Jan;13(1):181-4. doi: 10.1007/s00330-002-1650-5. Epub 2002 Sep 10.
8
Late-onset allergy-like reactions to X-ray contrast media.对X线造影剂的迟发性过敏样反应。
Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):333-9. doi: 10.1097/00130832-200208000-00007.
9
Fatal non-cardiogenic pulmonary oedema after intravenous non-ionic radiographic contrast.静脉注射非离子型放射造影剂后发生的致命性非心源性肺水肿。
Lancet. 2002 Mar 23;359(9311):1037-8. doi: 10.1016/s0140-6736(02)08068-6.
10
Delayed adverse reaction to nonionic contrast agents.非离子型造影剂的迟发性不良反应。
Pediatr Radiol. 2001 Aug;31(8):597-9. doi: 10.1007/s002470100483.