Division of Pulmonary and Critical Care, Department of Internal Medicine, Tannourine Governmental Hospital, Batroun, Lebanon.
Expert Rev Respir Med. 2013 Aug;7(4):429-37. doi: 10.1586/17476348.2013.814392.
The historic perspective that used to define chronic obstructive pulmonary disease has changed. As reviewed in this article, it is based on a better understanding of the underlying inflammatory airflow obstruction and a multidimensional classification, which mostly targets a subgroup called 'frequent exacerbators'. Clinical and radioimaging predictors are the stamina for an aggressive therapeutic approach. A simplified explanation of the updated Global Initiative for Obstructive Lung Disease guidelines will ease the burden of treatment selection.
慢性阻塞性肺疾病的历史定义已经发生了变化。本文综述了这一变化，其基础是对潜在炎症性气流阻塞和多维分类的更好理解，该分类主要针对所谓的“频繁加重者”亚组。临床和放射影像学预测指标是积极治疗方法的耐力。对更新后的全球阻塞性肺病倡议指南的简化解释将减轻治疗选择的负担。
