Gunka I, Samlík J, Mazur M, Pokorná E, Kuman M, Kubisová M
Chirugická klinika FN Ostrava a Lékaiská fakulta Ostravské univerzity.
Rozhl Chir. 2013 Apr;92(4):201-4.
Intoxicated patients represent only a minimum of the total number of cadaveric donors; however, their significance within the transplant program in the Czech Republic has recently been emphasized in connection with the so-called methanol affair.
A retrospective analysis of methanol-poisoned patients who were declared brain-dead and subsequently underwent organ removal for transplantation purposes in the University Hospital Ostrava was performed. In cooperation with other transplant centres (Institute for Clinical and Experimental Medicine, Transplant Centre of the University Hospital Hradec Kráilové, Centre for Cardiovascular and Transplantation Surgery in Brno) the graft function, postoperative morbidity and mortality was evaluated.
During the study period (since September 2012), organs from three brain-dead donors as a result of methanol intoxication were retrieved in the Transplant Centre of the University Hospital Ostrava. Subsequently, six kidneys were transplanted (3 males, 3 females). Postoperative complications occurred in two patients (33.3%), one patient died (16.7%). In one case (16.7%), the graft failed. None of the graft recipients developed clinical or laboratory signs of methanol poisoning.
Death due to methanol intoxication is not a contraindication to organ donation, graft function and patient survival being comparable to organs from non-intoxicated donors.
醉酒患者在尸体供者总数中所占比例极小；然而，近期在捷克共和国，与所谓的甲醇事件相关，其在移植项目中的重要性得到了强调。
对在俄斯特拉发大学医院被判定脑死亡且随后为移植目的而进行器官摘除的甲醇中毒患者进行了回顾性分析。与其他移植中心（临床与实验医学研究所、赫拉德茨 - 克拉洛韦大学医院移植中心、布尔诺心血管与移植外科中心）合作，对移植物功能、术后发病率和死亡率进行了评估。
在研究期间（自2012年9月起），俄斯特拉发大学医院移植中心获取了3名因甲醇中毒导致脑死亡供者的器官。随后，6个肾脏被移植（3名男性，3名女性）。2例患者出现术后并发症（33.3%），1例患者死亡（16.7%）。1例（16.7%）移植物失功。移植受者均未出现甲醇中毒的临床或实验室征象。
甲醇中毒导致的死亡并非器官捐献的禁忌证，移植物功能和患者存活率与非中毒供者的器官相当。
