Georgetown Institute for Cognitive and Computational Sciences.
J Cogn Neurosci. 1997 Fall;9(5):664-86. doi: 10.1162/jocn.1997.9.5.664.
In this study, changes in blood oxygenation and volume were monitored while monolingual right-handed subjects read English sentences. Our results confirm the role of the left peri-sylvian cortex in language processing. Interestingly, individual subject analyses reveal a pattern of activation characterized by several small, limited patches rather than a few large, anatomically well-circumscribed centers. Between-subject analyses confirm a lateralized pattern of activation and reveal active classical language areas including Broca's area, Wernicke's area, and the angular gyms. In addition they point to areas only more recently considered as language-relevant including the anterior portion of the superior temporal sulcus. This area has not been reliably observed in imaging studies of isolated word processing. This raises the hypothesis that activation in this area is dependent on processes specific to sentence reading.
在这项研究中，我们监测了单语右利手受试者阅读英语句子时的血氧变化和体积变化。我们的结果证实了左侧大脑外侧裂周皮层在语言处理中的作用。有趣的是，个体受试者分析显示出一种激活模式，其特征是几个小的、有限的斑块，而不是几个大的、解剖上界限明确的中心。组间分析证实了激活的偏侧化模式，并揭示了活跃的经典语言区域，包括布罗卡区、韦尼克区和角回。此外，它们还指向了最近才被认为与语言相关的区域，包括颞上沟的前部。在孤立单词处理的成像研究中，这个区域并没有被可靠地观察到。这就提出了一个假设，即该区域的激活依赖于句子阅读特有的过程。
