Mixon William, Angelle Patricea Patsy, Chang Richard I
The Compounding Pharmacy, Hickory, North Carolina.
Int J Pharm Compd. 2009 Nov-Dec;11(6):506-15.
Tears-which contain fibronectin, growth facors, and vitamins that support the migration, proliferation, and differentiation of the conjunctival and corneal epithelium-nourish, protect, and refresh the eye. An inadequate tear film produces a variety of symptoms (ocular irritation, itching, burning, eye strain or fatigue, photophobia, a foreign-body sensation, a sharp stabbing pain, blurred vision) that wax and wane in intensity and are characteristic of disorders such as dry eye (keratoconjunctivitis sicca) and neurotrophic keratitis. In patients for whom commercially manufactured eye drops fail to provide relief from the symptoms of those conditions, autologous serum eye drops (plasma eye drops, serum eye drops) have proven very effective. In this report, we examine the present case studies that reveal the efects of autologous serum eye drops on the signs and symptoms of both dry eye and neurotrophic keratitis. A procedure for preparing autologous eye drops is included.
眼泪中含有纤连蛋白、生长因子和维生素，这些物质能支持结膜和角膜上皮细胞的迁移、增殖和分化，起到滋养、保护和使眼睛清爽的作用。泪膜不足会产生多种症状（眼部刺激感、瘙痒、灼烧感、眼疲劳、畏光、异物感、刺痛、视力模糊），这些症状的强度会有波动，是干眼症（角结膜干燥症）和神经营养性角膜炎等疾病的特征。对于那些使用市售眼药水无法缓解这些症状的患者，自体血清眼药水（血浆眼药水、血清眼药水）已被证明非常有效。在本报告中，我们研究了目前的病例研究，这些研究揭示了自体血清眼药水对干眼症和神经营养性角膜炎的体征和症状的影响。文中还包括了一种制备自体眼药水的方法。
