揭示三阴性乳腺癌中的靶向治疗机会：一种新策略。 - Suppr

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超能文献

Revealing targeted therapeutic opportunities in triple-negative breast cancers: a new strategy.

作者信息

Poage Graham M, Hartman Zachary C, Brown Powel H

机构信息

Department of Clinical Cancer Prevention; The University of Texas MD Anderson Cancer Center; Houston, TX USA.

出版信息

Cell Cycle. 2013 Sep 1;12(17):2705-6. doi: 10.4161/cc.25871. Epub 2013 Jul 30.

DOI:10.4161/cc.25871

PMID:23966168

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3899176/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e826/3899176/a49c1350c444/cc-12-2705-g1.jpg

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本文引用的文献

Cancer Res. 2013 Jun 1;73(11):3470-80. doi: 10.1158/0008-5472.CAN-12-4524-T. Epub 2013 Apr 30.

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Nature. 2012 Oct 4;490(7418):61-70. doi: 10.1038/nature11412. Epub 2012 Sep 23.

Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population.IL6 炎症环的激活通过扩大癌症干细胞群体介导曲妥珠单抗耐药性在 HER2+乳腺癌中。

Mol Cell. 2012 Aug 24;47(4):570-84. doi: 10.1016/j.molcel.2012.06.014. Epub 2012 Jul 19.

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.2000 个乳腺肿瘤的基因组和转录组结构揭示了新的亚群。

Nature. 2012 Apr 18;486(7403):346-52. doi: 10.1038/nature10983.

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The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.JAK2/STAT3 信号通路对于人肿瘤中 CD44+CD24- 干细胞样乳腺癌细胞的生长是必需的。

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