Institute of Urology and Nephrology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
PLoS One. 2013 Aug 13;8(8):e71298. doi: 10.1371/journal.pone.0071298. eCollection 2013.
While many investigators have studied symptomatic prostatitis, little research has been done with regard to asymptomatic (NIH-IV) prostatitis.
To describe the prevalence of and risk factors for NIH-IV prostatitis among a large male population.
The study population was comprised of 1,868 men at the second phase recruitment of a population-based cohort in China. Asymptomatic and symptomatic men were defined by the National Institutes of Health Chronic Prostatitis (CP) Symptom Index. Meanwhile, EPS specimens and their leukocyte count were collected. Lifestyle and demographic characteristics were obtained through a questionnaire.
Prevalence of NIH-IV prostatitis was 21.1% among 1,868 asymptomatic men aged 19-78 years and increased with age. After adjusteing for potential confounding variables (age, smoking habits, alcohol drinking habits, education, physical activity, hypertension, dyslipidemia, obesity and diabetes), age remained a significant factor for NIH-IV prostatitis (OR = 1.35; 95% CI = 1.06-1.71; P = 0.01) and the risk of NIH-IV prostatitis was significantly higher in smokers≧15 pack/years than non-smokers (OR = 1.33; 95% CI = 1.01-1.75; P = 0.03). In addition, compared with non-drinkers, the OR of NIH-IV prostatitis in drinkers ≧1 drinks/week was 1.35 (95% CI = 1.03, 1.77, p = 0.02) after adjusting for the other variables above. In addition, having less than a college education may be a risk factor for NIH-IV prostatitis, although a statistically significant difference did not exist in our data (OR = 1.22; 95% CI = 0.97-1.52; P = 0.08).
Our findings suggest that NIH-IV prostatitis is prevalent in China. Age, smoking, drinking and lower education levels were associated with an increased risk of NIH-IV prostatitis. The prevalence of NIH-IV prostatitis should be taken into account when estimating the total prevalence of CP in future studies.
虽然许多研究人员已经研究了有症状的前列腺炎，但对于无症状（NIH-IV）前列腺炎的研究却很少。
描述中国一个大型男性人群中 NIH-IV 前列腺炎的患病率和危险因素。
研究人群由中国一项基于人群队列的第二阶段招募的 1868 名男性组成。无症状和有症状的男性通过 NIH 慢性前列腺炎症状指数来定义。同时，采集 EPS 标本并计数白细胞。通过问卷获得生活方式和人口统计学特征。
在 1868 名年龄在 19-78 岁的无症状男性中，NIH-IV 前列腺炎的患病率为 21.1%，并随年龄增长而增加。在校正潜在混杂因素（年龄、吸烟习惯、饮酒习惯、教育程度、体力活动、高血压、血脂异常、肥胖和糖尿病）后，年龄仍然是 NIH-IV 前列腺炎的一个显著因素（OR=1.35；95%CI=1.06-1.71；P=0.01），并且吸烟≧15 包/年的男性患 NIH-IV 前列腺炎的风险明显高于不吸烟者（OR=1.33；95%CI=1.01-1.75；P=0.03）。此外，与不饮酒者相比，调整上述其他变量后，每周饮酒≧1 杯的 NIH-IV 前列腺炎的 OR 为 1.35（95%CI=1.03，1.77，p=0.02）。此外，虽然在我们的数据中没有统计学意义，但受教育程度较低可能是 NIH-IV 前列腺炎的一个危险因素（OR=1.22；95%CI=0.97-1.52；P=0.08）。
我们的研究结果表明，NIH-IV 前列腺炎在中国很常见。年龄、吸烟、饮酒和较低的教育水平与 NIH-IV 前列腺炎的风险增加相关。在未来的研究中，估计 CP 的总患病率时应考虑 NIH-IV 前列腺炎的患病率。
