CT 血管造影显示肝细胞癌的异位血供：与形态学特征和治疗史的关系。
Ectopic blood supply of hepatocellular carcinoma as depicted by angiography with computed tomography: associations with morphological features and therapeutic history.
机构信息
Department of Radiology, Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
出版信息
PLoS One. 2013 Aug 15;8(8):e71942. doi: 10.1371/journal.pone.0071942. eCollection 2013.
OBJECTIVE
To investigate the associations of ectopic blood supply of hepatocellular carcinoma (HCC) with its morphological features and therapeutic history.
METHODS
Three hundred and six patients with 373 HCC lesions were enrolled in this study, and underwent biphasic contrast-enhanced scans on a 64-section MDCT. The anatomy of ectopic blood supply, morphological characteristics of HCC including the size, location and pseudocapsule, and history of transcatheter arterial chemoembolization (TACE) therapy were quantitively assessed and statistically analyzed.
RESULTS
Ectopic blood supply was found in 30.8% (115/373) lesions. The ectopic arteries were predominantly composed of inferior phrenic artery (86/115) followed by left and right gastric artery (25/115). Tumor size, location, status of pseudocapsule, and history of TACE therapy could impact the origination of ectopic arteries (all p<0.05).
CONCLUSION
The ectopic feeding arteries of HCC predominantly composed of the perihepatic arteries are associated with the morphological features of the tumor and therapeutic history.
目的
探讨肝细胞癌（HCC）异位血供与肿瘤形态学特征及治疗史的关系。
方法
本研究纳入 306 例 373 个 HCC 病灶患者，行 64 层 MDCT 双期增强扫描。定量评估并统计分析异位血供的解剖学、HCC 的形态学特征（包括大小、位置和假包膜）以及经导管动脉化疗栓塞（TACE）治疗史。
结果
115 个病灶（30.8%）存在异位血供，异位动脉主要来源于膈下动脉（86/115），其次为胃左、右动脉（25/115）。肿瘤大小、位置、假包膜状态和 TACE 治疗史均与异位动脉的起源有关（均 P<0.05）。
结论
HCC 的异位供养动脉主要来源于肝周动脉，与肿瘤的形态学特征和治疗史有关。
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