Ender L A, Vatazin A V, Abakumova L Ia, Denisova I V, Tsyplokova G Iu
Anesteziol Reanimatol. 1990 May-Jun(3):56-9.
The results of the application of exchange plasmapheresis in 51 patients with suppurative peritonitis have been processed statistically using "MEDSTAT-85" software. 2-3 exchange plasmapheresis procedures at an up to 2-day interval, with exfusion of 1000-1200 ml plasma and adequate replacement of plasma loss by freshly frozen donor plasma and specific hyperimmune plasma were shown to be an optimum regimen. Blood toxicity, concentration of medium molecular toxins and leukocytic index of intoxication were the most informative criteria of the efficacy of exchange plasmapheresis.
运用“MEDSTAT - 85”软件对51例化脓性腹膜炎患者进行血浆置换术的应用结果进行了统计学处理。结果表明,每间隔1至2天进行2至3次血浆置换术,每次置换出1000 - 1200毫升血浆,并通过新鲜冷冻的供血者血浆和特异性超免疫血浆充分补充血浆丢失量,这是最佳治疗方案。血液毒性、中分子毒素浓度和白细胞中毒指数是血浆置换术疗效最具参考价值的标准。