Naumenko S E
Anesteziol Reanimatol. 1990 May-Jun(3):63-6.
Craniocerebral hypothermia was used during open-heart surgery in 69 patients with mitral stenosis (hospital mortality rate 2.9%). Indications for open-heart surgery (left atrial thrombosis, mitral valve calcinosis, onset of traumatic mitral insufficiency) were determined intraoperatively during closed mitral commissurotomy. Some pathophysiological peculiarities of craniocerebral hypothermia were studied. A decrease in brain temperature and total oxygen consumption (up to 27.7% of the basic metabolism level) has been observed. Prolongation (up to 25 min) of major vessel occlusion had no negative effect on the patients' condition, postoperative complications and lethality. Craniocerebral hypothermia is considered to be a safe and effective technique indicated in case of emergency for open-heart surgery.
69例二尖瓣狭窄患者在心脏直视手术中采用了颅脑低温治疗(医院死亡率为2.9%)。心脏直视手术的指征(左心房血栓形成、二尖瓣钙化、创伤性二尖瓣关闭不全的发生)是在闭式二尖瓣交界切开术中术中确定的。研究了颅脑低温的一些病理生理特性。观察到脑温降低和总氧耗量降低(降至基础代谢水平的27.7%)。主要血管阻断时间延长(长达25分钟)对患者病情、术后并发症和死亡率没有负面影响。颅脑低温被认为是心脏直视手术紧急情况下一种安全有效的技术。