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闭式二尖瓣交界切开术后17年随访研究(作者译)

[A 17-years follow-up study after closed mitral commissurotomy (author's transl)].

作者信息

Haerten K, Raiber M, Seipel L, Loogen F

出版信息

Z Kardiol. 1980 Sep;69(9):618-24.

PMID:7210769
Abstract

410 patients were operated upon by closed mitral commissurotomy in 1961-62. Of this group, 224 patients were followed up until 1978. The actuarial survival rate after 16 to 17 years postoperatively was 58%. Overall 43 patients were reoperated (second commissurotomy or mitral valve replacement). The cumulative reoperation rate of these patients was 1.5% per year. The mortality rate in patients with reoperation was 1.2% per year, without reoperation 2% per year. 87 patients are still alive 17 years after mitral commissurotomy without reoperation. 59% of this group belong to functional class II or I (NYHA). Most of them have combined mitral valve disease with predominant mitral stenosis. Atrial fibrillation was present in 33% (n = 29) preoperatively and in 58% (n = 50) postoperatively at the end of the study. Only 20% of all patients were on anticoagulant therapy. Nevertheless, the total embolic rate (5.7%) and the cumulative embolic rate (0.2% per year) remained low. The good long-term results show that mitral commissurotomy is an effective therapeutic approach in patients with mitral stenosis.

摘要

1961年至1962年期间,410例患者接受了闭式二尖瓣交界切开术。在这组患者中,224例患者随访至1978年。术后16至17年的精算生存率为58%。总体上有43例患者接受了再次手术(二次交界切开术或二尖瓣置换术)。这些患者的累积再次手术率为每年1.5%。再次手术患者的死亡率为每年1.2%,未再次手术患者的死亡率为每年2%。87例患者在二尖瓣交界切开术后17年未再次手术仍存活。该组中59%的患者属于心功能II级或I级(纽约心脏病协会分级)。他们大多数合并二尖瓣疾病,以二尖瓣狭窄为主。术前33%(n = 29)的患者存在房颤,研究结束时术后为58%(n = 50)。所有患者中只有20%接受抗凝治疗。然而,总的栓塞率(5.7%)和累积栓塞率(每年0.2%)仍然较低。良好的长期结果表明,二尖瓣交界切开术是二尖瓣狭窄患者的一种有效治疗方法。

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