Darbinian T M, Zatevakhina M V, Abramushkina N P, Kuznetsova B A, Pugonin E V
Anesteziol Reanimatol. 1990 May-Jun(3):9-13.
Three techniques of general intravenous anesthesia were compared, using mathematical parameters of the heart rhythm, hemodynamic and sympathoadrenal system responses, arterial blood Hb saturation with O2 (SaO2) and thermometry. It has been established that anesthesia with dipidolor ensures adequate protection against the operation stress both in patients with tetralogy of Fallot previously subject to interarterial anastomoses and patients with tetralogy of Fallot without anastomoses. Combined fentanyl and ketamine anesthesia ensures an adequate protection against the operation stress only in patients with tetralogy of Fallot without anastomoses. A more marked response of sympathetic autonomous nervous system and hemodynamics in patients with tetralogy of Fallot previously subject to anastomoses is, probably, mediated by a more intensive analgesic sequestration in the lungs in the presence of functioning anastomoses, which attenuates the analgetic effect. Anesthesia in patients with tetralogy of Fallot previously subject to interaortic anastomoses should be performed using higher doses of narcotic analgesics.
采用心律、血流动力学和交感肾上腺系统反应、动脉血血红蛋白氧饱和度（SaO2）及体温测量等数学参数，对三种全身静脉麻醉技术进行了比较。结果表明，对于既往接受过动脉间吻合术的法洛四联症患者和未接受吻合术的法洛四联症患者，双氯芬酸麻醉均可确保对手术应激提供充分保护。芬太尼和氯胺酮联合麻醉仅对未接受吻合术的法洛四联症患者的手术应激提供充分保护。既往接受过吻合术的法洛四联症患者交感自主神经系统和血流动力学反应更为明显，这可能是由于存在功能性吻合时肺部更强的镇痛作用减弱了镇痛效果。对于既往接受过主动脉间吻合术的法洛四联症患者，应使用更高剂量的麻醉性镇痛药进行麻醉。
