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短潜伏期瞬态诱发耳声发射作为听力状况和阈值的预测指标。

Short-latency transient-evoked otoacoustic emissions as predictors of hearing status and thresholds.

机构信息

Department of Communication Sciences and Disorders, University of Iowa, Iowa City, Iowa 52242, USA.

出版信息

J Acoust Soc Am. 2013 Sep;134(3):2127-35. doi: 10.1121/1.4817831.

DOI:10.1121/1.4817831
PMID:23967943
Abstract

Estimating audiometric thresholds using objective measures can be clinically useful when reliable behavioral information cannot be obtained. Transient-evoked otoacoustic emissions (TEOAEs) are effective for determining hearing status (normal hearing vs hearing loss), but previous studies have found them less useful for predicting audiometric thresholds. Recent work has demonstrated the presence of short-latency TEOAE components in normal-hearing ears, which have typically been eliminated from the analyses used in previous studies. The current study investigated the ability of short-latency components to predict hearing status and thresholds from 1-4 kHz. TEOAEs were measured in 77 adult ears with thresholds ranging from normal hearing to moderate sensorineural hearing loss. Emissions were bandpass filtered at center frequencies from 1 to 4 kHz. TEOAE waveforms were analyzed within two time windows that contained either short- or long-latency components. Waveforms were quantified by root-mean-square amplitude. Long-latency components were better overall predictors of hearing status and thresholds, relative to short-latency components. There were no significant improvements in predictions when short-latency components were included with long-latency components in multivariate analyses. The results showed that short-latency TEOAE components, as analyzed in the current study, were less predictive of both hearing status and thresholds from 1-4 kHz than long-latency components.

摘要

当无法获得可靠的行为信息时,使用客观测量来估计听阈在临床上可能是有用的。瞬态诱发耳声发射(TEOAEs)可有效确定听力状况(正常听力与听力损失),但先前的研究发现,它们对于预测听阈的作用不大。最近的研究表明,正常听力耳中存在短潜伏期 TEOAE 成分,而这些成分通常已从先前研究中使用的分析中消除。本研究旨在探讨短潜伏期成分在预测 1-4 kHz 听阈和听力状况方面的能力。对 77 只成人耳朵进行了 TEOAE 测量,这些耳朵的阈值范围从正常听力到中度感音神经性听力损失。在中心频率为 1 至 4 kHz 的带宽下对 TEOAEs 进行带通滤波。在包含短潜伏期或长潜伏期成分的两个时间窗口内对 TEOAE 波形进行分析。通过均方根幅度对波形进行量化。与短潜伏期成分相比,长潜伏期成分总体上是听力状况和阈值的更好预测因子。在多元分析中,当将短潜伏期成分与长潜伏期成分结合使用时,预测并无显著改善。结果表明,与长潜伏期成分相比,当前研究中分析的短潜伏期 TEOAE 成分对 1-4 kHz 的听力状况和阈值的预测能力均较弱。

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