长春花生物碱及相关化合物的合成，XLIV：三氟阿朴长春胺酸酯的合成。
Synthesis of vinca alkaloids and related compounds, XLIV: Synthesis of trifluoro-apovincaminic acid ester.
作者信息
Incze M, Sóti F, Kardos-Balogh Z, Kajtár-Peredy M, Szántay C
机构信息
Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest.
出版信息
Arch Pharm (Weinheim). 1990 Jun;323(6):331-3. doi: 10.1002/ardp.19903230604.
PMID:2396892
Abstract
Via the intermediate iminium salt 8 the 21,21,21-trifluoro-apovincaminic acid ethyl ester (2), a derivative of CAVINTONR (1) was synthesized. The pharmacological effect of 2 changed dramatically compared with the parent compound.
摘要
通过中间体亚胺盐8合成了CAVINTONR（1）的衍生物21,21,21-三氟阿朴长春胺酸乙酯（2）。与母体化合物相比，2的药理作用发生了显著变化。
Zotero 插件