Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, USA; Clinical Research Programs, Sheppard Pratt Health System, Baltimore, MD, USA.
Psychiatry Res. 2013 Oct 30;209(3):273-8. doi: 10.1016/j.psychres.2013.07.044. Epub 2013 Aug 20.
This study examined the response to cannabis withdrawal symptoms and use of quitting strategies to maintain abstinence in people with schizophrenia. A convenience sample of 120 participants with schizophrenia who had at least weekly cannabis use and a previous quit attempt without formal treatment were administered the 176-item Marijuana Quit Questionnaire to characterize their "most serious" (self-defined) quit attempt. One hundred thirteen participants had withdrawal symptoms, of whom 104 (92.0%) took some action to relieve a symptom, most commonly nicotine use (75%). 90% of withdrawal symptoms evoked an action for relief in a majority of participants experiencing them, most frequently anxiety (95.2% of participants) and cannabis craving (94.4%). 96% of participants used one or more quitting strategies to maintain abstinence during their quit attempt, most commonly getting rid of cannabis (72%) and cannabis paraphernalia (67%). Religious support or prayer was the quitting strategy most often deemed "most helpful" (15%). Use of a self-identified most helpful quitting strategy was associated with significantly higher one-month (80.8% vs. 73.6%) and one-year (54.9% vs. 41.3%) abstinence rates. Actions to relieve cannabis withdrawal symptoms in people with schizophrenia are common. Promotion of effective quitting strategies may aid relapse prevention.
本研究旨在探讨精神分裂症患者在戒断大麻症状和使用戒烟策略以保持戒断方面的反应。通过便利抽样，对 120 名至少每周使用大麻且未经正式治疗即尝试过戒烟的精神分裂症患者进行了 176 项大麻戒断问卷的测试，以描述他们“最严重”（自我定义）的戒烟尝试。有 113 名参与者出现了戒断症状，其中 104 名（92.0%）采取了某种行动来缓解症状，最常见的是使用尼古丁（75%）。在经历这些症状的大多数参与者中，有 90%的戒断症状会引发缓解症状的行动，最常见的是焦虑（95.2%的参与者）和大麻渴望（94.4%）。96%的参与者在戒烟尝试期间使用了一种或多种戒烟策略来保持戒断，最常见的是戒除大麻（72%）和大麻用具（67%）。宗教支持或祈祷是最常被认为“最有帮助”的戒烟策略（15%）。使用自我认定的最有帮助的戒烟策略与更高的一个月（80.8%比 73.6%）和一年（54.9%比 41.3%）的戒断率显著相关。缓解精神分裂症患者大麻戒断症状的行为很常见。促进有效的戒烟策略可能有助于预防复发。
