Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA.
Am J Drug Alcohol Abuse. 2010 Nov;36(6):311-9. doi: 10.3109/00952990.2010.503825. Epub 2010 Aug 3.
Cannabis withdrawal can be a negative reinforcer for relapse, but little is known about its association with demographic characteristics.
Evaluate the association of demographic characteristics with the experience of cannabis withdrawal.
Retrospective self-report of a "serious" cannabis quit attempt without formal treatment in a convenience sample of 104 non-treatment-seeking, adult cannabis smokers (mean age 35 years, 52% white, 78% male) with no other current substance use disorder (except tobacco) or chronic health problems. Reasons for quitting, coping strategies to help quit, and 18 specific withdrawal symptoms were assessed by questionnaire.
Among withdrawal symptoms, only anxiety, increased sex drive, and craving showed significant associations with age, race, or sex. Women were more likely than men to report a physical withdrawal symptom (OR = 3.2, 95% CI = .99-10.4, p = .05), especially upset stomach. There were few significant demographic associations with coping strategies or reasons for quitting.
This small study suggests that there are few robust associations between demographic characteristics and cannabis withdrawal. Future studies with larger samples are needed. Attention to physical withdrawal symptoms in women may help promote abstinence.
大麻戒断可能是复吸的负强化因素，但人们对其与人口统计学特征的关系知之甚少。
评估人口统计学特征与大麻戒断体验的关联。
在一个方便的样本中，对 104 名未接受治疗的成年大麻吸烟者（平均年龄 35 岁，52%为白人，78%为男性）进行回顾性自我报告，这些人没有接受过正式治疗，且尝试过“严重”的大麻戒断。这些参与者没有其他当前的物质使用障碍（除了烟草）或慢性健康问题。通过问卷评估了戒烟原因、帮助戒烟的应对策略以及 18 种特定的戒断症状。
在戒断症状中，只有焦虑、性欲增加和渴望与年龄、种族或性别有显著关联。女性比男性更有可能报告身体戒断症状（OR = 3.2，95%CI =.99-10.4，p =.05），尤其是胃部不适。应对策略或戒烟原因与人口统计学特征之间几乎没有显著关联。
这项小型研究表明，人口统计学特征与大麻戒断之间几乎没有很强的关联。需要更大样本量的未来研究。关注女性的身体戒断症状可能有助于促进戒除。
