肝线粒体后上清液将L-[1-¹⁴C]亮氨酸掺入蛋白质的过程：预孵育的烟酰胺腺嘌呤二核苷酸磷酸和4-二甲基氨基-3'-甲基偶氮苯的相反作用。
Incorporation of L-[1-14C]leucine into protein by liver postmitochondrial supernatant: opposing effects of preincubated nicotinamide-adenine dinucleotide phosphate and 4-dimethylamino-3'-methylazobenzene.
作者信息
Madsen N P, Labuc J E
出版信息
Biochem J. 1975 Feb;146(2):505-7. doi: 10.1042/bj1460505.
Abstract
Combination of preincubated drug-metabolizing medium containing NADP+ with a cell-free protein-synthesizing system resulted in marked stimulation of incorporation of L-[1-14C]leucine into protein. Addition of 4-dimethylamino-3'-methylazobenzene, present and previously preincubated in the drug-metabolizing medium, decreased this effect.
摘要
含有NADP⁺的预孵育药物代谢介质与无细胞蛋白质合成系统相结合，导致L-[1-¹⁴C]亮氨酸掺入蛋白质的过程受到显著刺激。在药物代谢介质中存在并预先孵育的4-二甲基氨基-3'-甲基偶氮苯的添加降低了这种效应。
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