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Strong association of the SNP rs17822931 with wet earwax and bromhidrosis in a Chinese family.

作者信息

Shang Dandan, Zhang Xue, Sun Miao, Wei Yang, Wen Yaran

机构信息

Department of Biochemistry and Molecular Biology, Hebei Key Laboratory of Medical Biotechnology, Hebei Medical University, Shijiazhuang, Hebei Province 050017, People's Republic of China.

出版信息

J Genet. 2013;92(2):289-91. doi: 10.1007/s12041-013-0229-z.

DOI:10.1007/s12041-013-0229-z
PMID:23970085
Abstract
摘要

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Strong association of the SNP rs17822931 with wet earwax and bromhidrosis in a Chinese family.
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Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?耳垢、腋臭与乳腺癌：为何人类ABC转运蛋白ABCC11基因中的一个单核苷酸多态性（538G>A）决定了耳垢类型？
FASEB J. 2009 Jun;23(6):2001-13. doi: 10.1096/fj.09-129098. Epub 2009 Apr 21.
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[Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese Han population].[ABCC11基因单核苷酸多态性与中国汉族人群腋臭发病率的相关性]
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The impact of natural selection on an ABCC11 SNP determining earwax type.自然选择对决定耳垢类型的 ABCC11 SNP 的影响。
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A SNP in the ABCC11 gene is the determinant of human earwax type.ABCC11基因中的一个单核苷酸多态性是人类耳垢类型的决定因素。
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Correlation of axillary osmidrosis to a SNP in the ABCC11 gene determined by the Smart Amplification Process (SmartAmp) method.通过 SmartAmp 方法确定的 ABCC11 基因单核苷酸多态性与腋窝多汗症的相关性。
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Allele frequencies of a SNP and a 27-bp deletion that are the determinant of earwax type in the ABCC11 gene.单核苷酸多态性（SNP）和一个27碱基对缺失的等位基因频率，这两个因素决定了ABCC11基因中的耳垢类型。
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A missense variant of the ABCC11 gene is associated with Axillary Osmidrosis susceptibility and clinical phenotypes in the Chinese Han Population.ABCC11 基因的错义变异与中国人腋臭易感性及临床表型相关。
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本文引用的文献

1
A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland.人类耳垢类型与乳腺顶泌初乳分泌之间存在密切关联。
Hum Genet. 2007 Jun;121(5):631-3. doi: 10.1007/s00439-007-0356-9. Epub 2007 Mar 30.
2
A SNP in the ABCC11 gene is the determinant of human earwax type.ABCC11基因中的一个单核苷酸多态性是人类耳垢类型的决定因素。
Nat Genet. 2006 Mar;38(3):324-30. doi: 10.1038/ng1733. Epub 2006 Jan 29.
3
The dimorphism in human normal cerumen.人类正常耵聍的二态性。
Ann Hum Genet. 1962 May;25:273-86. doi: 10.1111/j.1469-1809.1962.tb01766.x.
4
Histopathology of apocrine bromhidrosis.顶泌汗腺性臭汗症的组织病理学
Plast Reconstr Surg. 1996 Aug;98(2):288-92. doi: 10.1097/00006534-199608000-00012.
5
The microbiology of the human axilla and its relationship to axillary odor.人类腋窝的微生物学及其与腋臭的关系。
J Invest Dermatol. 1981 Nov;77(5):413-6. doi: 10.1111/1523-1747.ep12494624.
6
Morphological differences between secretory cells of wet and dry types of human ceruminous glands.人类耵聍腺干湿两种类型分泌细胞的形态学差异
Am J Anat. 1988 Apr;181(4):377-84. doi: 10.1002/aja.1001810405.
7
Cerumen phenotype and proliferative epithelium in breast fluids of U.S.-born vs. immigrant Asian women: a possible genetic-environmental interaction.
Breast Cancer Res Treat. 1990 Oct;16(3):279-85. doi: 10.1007/BF01806336.