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一名系统性红斑狼疮患者出现1型单纯疱疹病毒性脑炎及罕见视网膜病变。

Herpes simplex virus type 1 encephalitis and unusual retinitis in a patient with systemic lupus erythematosus.

作者信息

Zhang L, Liu J J, Li M T

机构信息

Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, China.

出版信息

Lupus. 2013 Nov;22(13):1403-8. doi: 10.1177/0961203313502112. Epub 2013 Aug 22.

DOI:10.1177/0961203313502112
PMID:23970491
Abstract

In this report we discuss a case of a patient with systemic lupus erythematosus who developed herpes simplex virus type 1(HSV-1) infection presenting with encephalitis as well as necrotic and non-necrotic retinitis. The patient presented with typical clinical symptoms and radiologic abnormalities consistent with HSV-1 encephalitis and HSV-1 retinitis in patients with HIV infection, but lacked cerebrospinal fluid pleocytosis and had bilateral retinitis with poor visual acuity. To the best of our knowledge, this is the first such case reported in the literature.

摘要

在本报告中,我们讨论了一例系统性红斑狼疮患者,该患者发生了1型单纯疱疹病毒(HSV-1)感染,表现为脑炎以及坏死性和非坏死性视网膜炎。该患者出现了与HIV感染患者的HSV-1脑炎和HSV-1视网膜炎一致的典型临床症状和影像学异常,但缺乏脑脊液细胞增多症,且患有双侧视网膜炎,视力较差。据我们所知,这是文献中首次报道的此类病例。

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