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Unraveling the mechanisms underlying olanzapine-induced insulin resistance.

作者信息

Irwin Nigel, Gault Victor Alan

机构信息

School of Pharmacy and Pharmaceutical Sciences, The SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, UK.

出版信息

Diabetes. 2013 Sep;62(9):3022-3. doi: 10.2337/db13-0804.

DOI:10.2337/db13-0804
PMID:23970523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3749356/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f17/3749356/21e3e427ab10/3022fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f17/3749356/21e3e427ab10/3022fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f17/3749356/21e3e427ab10/3022fig1.jpg

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本文引用的文献

1
Antipsychotic-induced insulin resistance and postprandial hormonal dysregulation independent of weight gain or psychiatric disease.抗精神病药引起的胰岛素抵抗和餐后激素失调与体重增加或精神疾病无关。
Diabetes. 2013 Sep;62(9):3232-40. doi: 10.2337/db13-0430. Epub 2013 Jul 8.
2
Antipsychotics associated with the development of type 2 diabetes in antipsychotic-naïve schizophrenia patients.抗精神病药与抗精神病药物初治精神分裂症患者 2 型糖尿病的发生相关。
Neuropsychopharmacology. 2010 Aug;35(9):1997-2004. doi: 10.1038/npp.2010.78. Epub 2010 Jun 2.
3
Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism.
Xenin-25 通过新型胆碱能中继机制增强葡萄糖依赖性胰岛素释放肽的作用。
J Biol Chem. 2010 Jun 25;285(26):19842-53. doi: 10.1074/jbc.M110.129304. Epub 2010 Apr 26.
4
Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets.短期奥氮平治疗不会调节肠道激素分泌:奥氮平分散片与标准片剂的比较。
Eur J Endocrinol. 2010 Jan;162(1):75-83. doi: 10.1530/EJE-09-0433. Epub 2009 Sep 24.
5
Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications.在肥胖相关性糖尿病中,受损的生长抑素作用具有有益效果的证据及其可能的治疗意义。
Diabetologia. 2009 Sep;52(9):1724-31. doi: 10.1007/s00125-009-1422-8. Epub 2009 Jun 17.
6
Incretin-based therapies for type 2 diabetes mellitus.用于2型糖尿病的基于肠促胰岛素的疗法。
Nat Rev Endocrinol. 2009 May;5(5):262-9. doi: 10.1038/nrendo.2009.48.
7
Incretin hormone mimetics and analogues in diabetes therapeutics.糖尿病治疗中的肠促胰岛素激素类似物
Best Pract Res Clin Endocrinol Metab. 2007 Dec;21(4):497-516. doi: 10.1016/j.beem.2007.09.003.
8
Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles.非典型抗精神病药物引起的代谢副作用:来自受体结合谱的见解。
Mol Psychiatry. 2008 Jan;13(1):27-35. doi: 10.1038/sj.mp.4002066. Epub 2007 Sep 11.
9
Adiposity and insulin sensitivity derived from intravenous glucose tolerance tests in antipsychotic-treated patients.抗精神病药物治疗患者静脉葡萄糖耐量试验得出的肥胖与胰岛素敏感性
Neuropsychopharmacology. 2007 Dec;32(12):2561-9. doi: 10.1038/sj.npp.1301392. Epub 2007 Mar 21.
10
A retrospective comparison of weight, lipid, and glucose changes between risperidone- and olanzapine-treated inpatients: metabolic outcomes after 1 year.利培酮与奥氮平治疗住院患者体重、血脂及血糖变化的回顾性比较:1年后的代谢结果
J Clin Psychiatry. 2002 May;63(5):425-33. doi: 10.4088/jcp.v63n0509.