Roman Arthur Dessi E, Salvaña Edsel Maurice T, Guzman-Peñamora Mary Ann J De, Roxas Evalyn A, Leyritana Katerina T, Saniel Mediadora C
Philippine General Hospital, University of the Philippines, Manila, Philippines.
Int J STD AIDS. 2014 Jan;25(1):70-5. doi: 10.1177/0956462413487716. Epub 2013 Jul 29.
Invasive Trichosporon infection is a rare, life-threatening infection in immunocompromised patients. It has been reported as an emerging opportunistic infection in those with acquired immune deficiency syndrome (AIDS). Only 12 cases of invasive trichosporonosis in patients with HIV have been documented, none in Southeast Asia. We report a case of fatal, disseminated trichosporonosis in a Filipino AIDS patient with severe cutaneous and pulmonary involvement. Invasive trichosporonosis should be considered in HIV-positive patients with disseminated fungal infection since this may be refractory to conventional antifungal treatment.
侵袭性毛孢子菌感染在免疫功能低下患者中是一种罕见的、危及生命的感染。据报道，它是获得性免疫缺陷综合征（AIDS）患者中一种新出现的机会性感染。仅有12例HIV患者发生侵袭性毛孢子菌病的病例被记录在案，东南亚地区尚无此类病例。我们报告1例菲律宾AIDS患者发生致命性播散性毛孢子菌病，伴有严重皮肤和肺部受累。对于发生播散性真菌感染的HIV阳性患者，应考虑侵袭性毛孢子菌病，因为其可能对传统抗真菌治疗无效。
