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一名患有艾滋病且出现尿脓毒症的患者在接受体外冲击波碎石术后发生播散性肺结核。

Disseminated tuberculosis after extracorporeal shock-wave lithotripsy in an AIDS patient presenting with urosepsis.

作者信息

Tourchi Ali, Ebadi Maryam, Hosseinzadeh Alireza, Shabaninia Mahsa

机构信息

Division of Pediatric Urology, Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

出版信息

Int J STD AIDS. 2014 Mar;25(3):231-4. doi: 10.1177/0956462413498580. Epub 2013 Aug 1.

Abstract

Haematogenous dissemination of undiagnosed urinary tuberculosis after performing extracorporeal shock-wave lithotripsy (ESWL) is extremely rare. Herein, we report a 41-year-old male who presented with urosepsis to the emergency room; catheterization was performed and retention resolved. He had a tattoo on his left arm and a five-year history of intravenous drug use. Blood tests indicated anaemia, leukocytosis, elevated CRP and ESR and mild hyponatraemia; haematuria, moderate bacteriuria and 2+ proteinuria on urinanalysis were observed. Chest X-ray revealed lesions suggestive of miliary tuberculosis, which was confirmed by chest CT scan. Brain CT and MRI suggested brain involvement in the setting of tuberculosis. On further investigations, HIV infection and hepatitis C seropositivity were detected and the patient remained in a coma for five days with a Glasgow Coma Scale of 6/15. Finally, the diagnosis of haematogenous dissemination of tuberculosis following lithotripsy was established. Anti-tuberculosis and anti-retroviral therapy were prescribed and monthly follow-up visits were scheduled. In conclusion, in a patient diagnosed with ureterolithiasis, a thorough history and physical examination, with specific attention to HIV and tuberculosis predisposing factors, should be carried out and preoperative screening tests considering the possibility of urinary tuberculosis are required. Finally, if urinary tuberculosis is detected, ESWL must be postponed until after appropriate treatment of tuberculosis.

摘要

体外冲击波碎石术(ESWL)后未诊断出的泌尿生殖系结核发生血行播散极为罕见。在此,我们报告一名41岁男性,因尿脓毒症急诊入院;进行了导尿,尿潴留得以缓解。他左臂有纹身且有5年静脉吸毒史。血液检查显示贫血、白细胞增多、CRP和ESR升高以及轻度低钠血症;尿液分析可见血尿、中度菌尿和2+蛋白尿。胸部X线显示有提示粟粒性结核的病变,胸部CT扫描证实了这一点。脑部CT和MRI提示结核累及脑部。进一步检查发现患者感染HIV且丙型肝炎血清学呈阳性,患者昏迷5天,格拉斯哥昏迷量表评分为6/15。最终,确诊为碎石术后结核血行播散。给予抗结核和抗逆转录病毒治疗,并安排每月随访。总之,对于诊断为输尿管结石的患者,应进行全面的病史和体格检查,特别关注HIV和结核易感因素,并且需要进行考虑泌尿生殖系结核可能性的术前筛查。最后,如果检测到泌尿生殖系结核,ESWL必须推迟至结核得到适当治疗之后。

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