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双重病变:诊断难题。

Dual lesions: a diagnostic dilemma.

作者信息

Prabhat M P V, Deshpande Prasannasrinivas, Gummadapu Sarat, Babburi Suresh, Chintamaneni Raja Lakshmi, Sujanamulk Bhavana

机构信息

Department of Oral Medicine and Radiology, Dr. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Krishna District, Gannavaram, Andhra Pradesh 521286, India.

出版信息

Case Rep Dent. 2013;2013:539234. doi: 10.1155/2013/539234. Epub 2013 Jul 18.

Abstract

Glandular odontogenic cyst (GOC) is a rare aggressive developmental cyst of the jaw. It most commonly occurs in middle-aged people with mandible anterior region being the most affected site. This lesion can present as a unilocular or multilocular radiolucency and has high recurrence rate. The histopathologic features of the GOC are complex and often coincide with the features of dentigerous cyst, radicular cyst, and low-grade central mucoepidermoid carcinoma (CMEC). At times, the microscopic features are so similar to central low-grade mucoepidermoid carcinoma that it becomes highly impossible to distinguish the two entities even with various advanced investigations. The reported case represents one such diagnostic dilemma occurring in the maxilla which is a rare site, and the lesion/s appeared as two distinct entities, that is, GOC and CMEC on either aspects of the same side of maxilla clinically, yet showing continuity on advanced imaging and demonstrating histopathological perplexity.

摘要

腺牙源性囊肿(GOC)是一种罕见的侵袭性颌骨发育性囊肿。它最常见于中年人,下颌前部区域是最常受累的部位。该病变可表现为单房或多房透射区,且复发率高。腺牙源性囊肿的组织病理学特征复杂,常与含牙囊肿、根尖囊肿和低级别中央型黏液表皮样癌(CMEC)的特征相符。有时,其微观特征与中央型低级别黏液表皮样癌非常相似,以至于即使进行各种先进检查也极难区分这两种病变。报告的该病例代表了发生在上颌骨这一罕见部位的此类诊断困境,病变在临床上表现为上颌骨同一侧的两个不同实体,即腺牙源性囊肿和黏液表皮样癌,但在先进影像检查中显示连续,且组织病理学表现令人困惑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cad1/3732642/8774caaa1caf/CRIM.DENTISTRY2013-539234.001.jpg

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