Faculty of Science and Engineering, School of Chemistry and the Environment, Division of Chemistry and Environmental Science, Manchester Metropolitan University, Chester Street, Manchester M15GD, Lancs, UK.
Analyst. 2013 Oct 21;138(20):6185-91. doi: 10.1039/c3an01352a. Epub 2013 Aug 23.
The electroanalytical sensing of Rohypnol® (flunitrazepam) is reported for the first time utilising screen-printed graphite electrodes without the requirement for any additional pre-treatment or modification. The methodology is shown to be useful for quantifying low levels (μg mL(-1)) of Rohypnol® in not only buffered solutions but also two internationally favoured drinks: Coca Cola™ and the alcopop WKD™ without any sample pre-treatment. The current analytical approaches for the sensing of Rohypnol® are also summarised within this paper. The niche of this electroanalytical protocol is the lack of the requirement of any pre-treatment of the sample/beverage or electrode modification (cleaning, pre-treatment etc.) for the determination of Rohypnol® in beverages and offers a potential rapid, cost-effective, yet suitably sensitive and accurate screening solution to the problem posed by coloured drinks to products such as the colour changing 'Smart Cup'.
本文首次报道了利用丝网印刷石墨电极无需任何额外的预处理或修饰即可检测氟硝西泮（罗眠乐，俗称“蓝精灵”）的电化学生物传感方法。该方法不仅可用于定量检测缓冲溶液中低浓度（μg/mL）的罗眠乐，还可用于未经任何样品预处理的两种国际流行饮料（可口可乐和沃克尔能量鸡尾酒）中的罗眠乐，无需对样品/饮料进行预处理。本文还总结了目前用于检测罗眠乐的分析方法。这种电化学生物传感方法的独特之处在于，在检测饮料中的罗眠乐时，无需对样品/饮料进行任何预处理或对电极进行修饰（清洁、预处理等），为变色“智能杯”等产品遇到的有色饮料问题提供了一种潜在的快速、经济高效、灵敏且准确的筛选解决方案。
