Ratnatunga C P, Barin E S, Manche A R, Davies D W, Nathan A W, Edmondson S J
Department of Cardiothoracic Surgery, St. Bartholomew's Hospital, London, UK.
Eur J Cardiothorac Surg. 1990;4(7):379-82; discussion 382-3. doi: 10.1016/1010-7940(90)90046-3.
Twenty-two consecutive patients underwent elective map-guided extensive endocardial resection (EER) for recurrent ventricular tachyarrhythmias (VT) of whom 20 were male. The ages ranged from 43 to 74 years (mean 57). All arrhythmias were ischaemic in origin. The mean ejection fraction was 29%. The presenting arrhythmias were ventricular tachycardia in 14, ventricular fibrillation (VF) alone in 1 and ventricular tachycardia and VF in 7. Useful additional intraoperative mapping was obtained in 19 patients. Under cardioplegic arrest, the scarred left (22) and where indicated right (4) ventricular endocardium was extensively resected. Resection of scarred papillary muscles was avoided and where indicated, localised cryoablation was performed: 21/22 had concomitant aneurysmectomy and/or coronary artery bypass grafting. There was 1 (4.5%) operative death. All survivors (95.5%) underwent postoperative electrophysiological studies at around 1 week. None had inducible arrhythmias. There were 3 (13.5%) late cardiac deaths, all due to primary cardiac failure without recurrence of arrhythmia. Of 17 (77%) long-term survivors, 16 (94%) are VT-free on no anti-arrhythmic medication at a mean follow-up of 37.2 months. One developed a new arrhythmia at 1 year which is controlled on medication. EER offers a high rate of success in ablating VT in association with a low operative mortality and good prospect of VT-free long-term survival.
22例连续患者因复发性室性心律失常接受了选择性标测引导下广泛心内膜切除术(EER),其中20例为男性。年龄范围为43至74岁(平均57岁)。所有心律失常均起源于缺血性。平均射血分数为29%。出现的心律失常中,14例为室性心动过速,1例仅为心室颤动(VF),7例为室性心动过速和VF。19例患者术中获得了有用的额外标测。在心脏停搏下,广泛切除了瘢痕化的左心室心内膜(22例),必要时切除右心室心内膜(4例)。避免切除瘢痕化的乳头肌,必要时进行局部冷冻消融:21/22例同时进行了动脉瘤切除术和/或冠状动脉旁路移植术。有1例(4.5%)手术死亡。所有幸存者(95.5%)在术后约1周接受了电生理检查。无一例诱发出心律失常。有3例(13.5%)晚期心脏死亡,均因原发性心力衰竭,无心律失常复发。17例(77%)长期幸存者中,16例(94%)在平均随访37.2个月时未服用抗心律失常药物且无室性心动过速。1例在1年时出现新的心律失常,药物治疗可控制。EER在消融室性心动过速方面成功率高,手术死亡率低,无室性心动过速长期生存前景良好。