J Acad Nutr Diet. 2013 Sep;113(9):1209-18. doi: 10.1016/j.jand.2013.05.027.
Malnutrition in hospitalized patients is associated with an increased risk of death and complications. The purpose of this study was to determine which nutrition-related risk index predicts mortality better in patients receiving total parenteral nutrition. This prospective, multicenter study involved noncritically ill patients who were prescribed total parenteral nutrition. Data were collected on Subjective Global Assessment (SGA), Nutritional Risk Index, Geriatric Nutritional Risk Index, body mass index, albumin and prealbumin, as well as in-hospital mortality, length of stay, and infectious complications. Of the 605 patients included in the study, 18.8% developed infectious complications and 9.6% died in the hospital. SGA, albumin, Nutritional Risk Index and Geriatric Nutritional Risk Index were associated with longer hospital stay. Prealbumin levels were associated with infectious complications. Multiple logistic regression analysis showed (after adjustment for age, sex, C-reactive protein levels, mean blood glucose levels, use of corticoids, prior comorbidity, carbohydrates infused, diagnosis, and infectious complications) that the SGA, Geriatric Nutritional Risk Index, body mass index, albumin, and prealbumin were associated with an increased risk for in-hospital mortality. SGA was the tool that best predicted mortality and adequately discriminated the values of the other nutrition-related risk indexes studied. The SGA is a clinically effective and simple tool for nutrition assessment in noncritically ill patients receiving total parenteral nutrition and detects the risk of inpatient mortality better than others.
住院患者营养不良与死亡和并发症风险增加有关。本研究旨在确定哪种与营养相关的风险指数在接受全肠外营养的患者中能更好地预测死亡率。这项前瞻性、多中心研究纳入了接受全肠外营养的非危重症患者。收集了主观全面评估(SGA)、营养风险指数、老年营养风险指数、体重指数、白蛋白和前白蛋白以及院内死亡率、住院时间和感染并发症的数据。在纳入研究的 605 名患者中,18.8%发生了感染并发症,9.6%在医院死亡。SGA、白蛋白、营养风险指数和老年营养风险指数与住院时间延长有关。前白蛋白水平与感染并发症有关。多变量逻辑回归分析显示(调整年龄、性别、C 反应蛋白水平、平均血糖水平、皮质激素使用、既往合并症、输注的碳水化合物、诊断和感染并发症后),SGA、老年营养风险指数、体重指数、白蛋白和前白蛋白与住院期间死亡风险增加有关。SGA 是预测死亡率的最佳工具,能够充分区分所研究的其他与营养相关的风险指数的值。SGA 是一种在接受全肠外营养的非危重症患者中进行营养评估的临床有效且简单的工具,比其他工具更能检测住院患者死亡风险。