Smith A J, Tobias R S, Plant C G, Browne R M, Lesot H, Ruch J V
University of Birmingham Dental School, St. Chads Queensway, UK.
Biomaterials. 1990 Jul;11:22-4.
Two fractions of isolated noncollagenous extracellular matrix proteins from dentine have been implanted into the base of exposed cavities in ferret canine teeth. After sealing the cavities, reparative dentinogenesis was assessed histologically after 14 and 28 days as compared to control cavities. Reparative dentinogenesis was enhanced in the presence of these matrix proteins with evidence of tubular dentine along the walls of the exposure and on the cavity floor demonstrating the in vivo morphogenetic properties of the dentine matrix proteins.
从牙本质中分离出的两部分非胶原细胞外基质蛋白已被植入雪貂犬齿暴露窝洞的底部。封闭窝洞后，与对照窝洞相比，在14天和28天后通过组织学评估修复性牙本质形成。在这些基质蛋白存在的情况下，修复性牙本质形成增强，暴露处壁和窝洞底部有管状牙本质的证据，证明了牙本质基质蛋白的体内形态发生特性。
