Hacettepe University, Faculty of Engineering, Department of Food Engineering, Beytepe Campus, 06800 Ankara, Turkey.
Spectrochim Acta A Mol Biomol Spectrosc. 2013 Dec;116:339-47. doi: 10.1016/j.saa.2013.07.071. Epub 2013 Aug 3.
Four newly synthesized poly (propylene amine) dendrimers from first and second generation modified with 1,8-naphthalimide units in the dendrimer periphery have been investigated as ligands for the detection of heavy metal ions (Al(3+), Sb(2+), As(2+), Cd(2+) and Pb(2+)) by surface-enhanced Raman spectroscopy. Calibration curves were established for all metal ions between the concentration ranges of 1 x 10(-6) to 5 x 10(-4) M. It has been shown that these dendrimers can be coordinated, especially with different metal ions. Using dendrimer molecules and silver colloids at the same time allowed us to obtain an SERS signal from the abovementioned metal ions at very low concentrations. Principle component analysis (PCA) analysis was also applied to the collected SERS data. Four different PCA models were developed to accomplish the discrimination of five metal ions, which interacted with each of the four dendrimer molecules, separately. A detailed investigation was performed in the present study to provide the basis of a new approach for heavy metal detection.
四种新型合成的聚（丙烯胺）树状大分子，第一代和第二代在树突状分子外围用 1,8-萘二酰亚胺单元修饰，被用作通过表面增强拉曼光谱法检测重金属离子（Al(3+)、Sb(2+)、As(2+)、Cd(2+)和 Pb(2+)）的配体。建立了所有金属离子在 1 x 10(-6) 到 5 x 10(-4) M 浓度范围内的校准曲线。结果表明，这些树突大分子可以与不同的金属离子配位。同时使用树突大分子和银胶体，我们可以在非常低的浓度下从上述金属离子中获得 SERS 信号。还对收集到的 SERS 数据应用了主成分分析（PCA）分析。开发了四个不同的 PCA 模型，以实现对与四种树突大分子分别相互作用的五种金属离子的区分。本研究进行了详细的研究，为重金属检测提供了一种新方法的基础。
