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欧洲某国多发性骨髓瘤和淋巴瘤患者外周血干细胞动员与采集的成本:意大利骨髓移植研究组(GITMO)和意大利血液成分单采与细胞处理协会(SIdEM)的调查结果

The costs of mobilisation and collection of peripheral blood stem cells in multiple myeloma and lymphoma in an European country: results from The Gruppo Italiano Trapianto Midollo Osseo (GITMO) and Società Italiana di Emaferesi e Manipolazione Cellulare (SIdEM) survey.

作者信息

Pierelli Luca, Berto Patrizia, Accorsi Patrizia, Milone Giuseppe, Lopatriello Stefania, Aiello Andrea, Iacopino Pasquale, Olivieri Attilio, Rambaldi Alessandro, Bosi Alberto

机构信息

Servizio di Immunoematologia e Trasfusionale, Azienda Ospedaliera San Camillo-Forlanini and Università di Roma-La Sapienza, Roma, Italy.

出版信息

Transfus Apher Sci. 2013 Dec;49(3):615-22. doi: 10.1016/j.transci.2013.07.025. Epub 2013 Aug 6.

Abstract

Scarce information is available about the cost of mobilisation/collection of peripheral blood stem cells for patients undergoing autologous transplant for relapsed Lymphoma or Multiple Myeloma. This paper reports the consumption of resources and costs collected through a survey among Italian Centres who adhere to the GITMO and SIdEM scientific societies. General transplant information was extracted from the European Promise database. Resources used alongside the phases of mobilisation/collection were retrieved. Resources for each of the process phases were quantified and averaged across centres and a unit cost value was attributed, based on administrative data from 3 centres, tariffs and market values. 25/89 Centres (34% of 2009 Promise transplants) provided data according to their standard practice. The mean cost/patient of the process of cell mobilisation/collection was € 6830 ± 1802 for Multiple Myeloma and € 7304 ± 1542 for Lymphoma. The organisational path for PBSC mobilisation/collection appears complex and cumbersome, spread amongst different treatment settings, with many different healthcare professionals being involved and considerable amounts of time and resources being currently dedicated to the management of patients requiring autologous transplantation.

摘要

关于复发淋巴瘤或多发性骨髓瘤患者进行自体移植时动员/采集外周血干细胞的成本,可获取的信息稀缺。本文报告了通过对意大利加入GITMO和SIdEM科学协会的中心进行调查所收集到的资源消耗和成本情况。一般移植信息从欧洲Promise数据库中提取。检索了动员/采集各阶段所使用的资源。对每个流程阶段的资源进行了量化,并在各中心进行平均,基于3个中心的行政数据、收费标准和市场价值赋予了单位成本值。25/89个中心(占2009年Promise移植的34%)按照其标准操作提供了数据。多发性骨髓瘤患者细胞动员/采集过程的平均成本为6830±€1802,淋巴瘤患者为7304±€1542。外周血干细胞动员/采集的组织流程似乎复杂且繁琐,分散在不同的治疗环节中,涉及许多不同的医疗专业人员,目前有大量时间和资源用于管理需要自体移植的患者。

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