Laboratory of Process Analysis and Design, Department of Chemical Engineering, National Technical University of Athens, Zografou Campus, 15780 Athens, Greece.
J Mech Behav Biomed Mater. 2013 Dec;28:147-55. doi: 10.1016/j.jmbbm.2013.07.013. Epub 2013 Jul 24.
Daily disinfection of maxillofacial prosthesis may reduce their service-life and lead to replacement.
The purpose of this study was to evaluate possible alterations in the mechanical behavior of two maxillofacial elastomers after application of four different disinfection procedures.
The materials tested were two maxillofacial elastomers, a commercially available polydimethylsiloxane (PDMS) and an experimental chlorinated polyethylene (CPE). Different disinfection procedures such as microwave exposure, hypochlorite solution, neutral soap and a commercially antimicrobial solution, were applied for a period which simulates one year of a real service life. Mechanical behavior was investigated through tensile and microindentation tests in various depths. Mathematical models were fitted to tensile curves. Alterations in tensile parameters (maximum stress, maximum strain, elasticity and viscoelasticity parameter) were subjected to two way ANOVA and Tukey's post hoc tests (α=.05).
Most of the tensile parameters presented significant alterations among different disinfection procedures and maxillofacial materials which became also harder. Microwave exposure caused greater changes in PDMS and CPE elastomer whereas commercial antimicrobial solution and neutral soap did not significantly affect them. Microindentation and tensile tests revealed similar changes in materials' elastic modulus and hardness whereas the observed changes were greater into smaller depths.
Tensile and microindentation properties of PDMS and CPE elastomers presented changes after disinfected with four different procedures. Changes in the surface of both materials were more intense than in the bulk of the materials. Microwave exposure affected most the two elastomers, so concerning the findings of this study is not recommended for the disinfection of the examined PDMS and CPE elastomers. Moreover, microwave exposure and hypochlorite solution caused greater changes in the surface (3μm) of CPE samples as indicated by microindentation results. PDMS affected less from the commercial antimicrobial agent and CPE from neutral soap, which seems to be the most suitable disinfection techniques.
每天对颌面修复体进行消毒可能会缩短其使用寿命并导致更换。
本研究旨在评估四种不同消毒程序对两种颌面弹性体的机械性能可能产生的影响。
测试的材料是两种颌面弹性体，一种是市售的聚二甲基硅氧烷（PDMS），另一种是实验用的氯化聚乙烯（CPE）。不同的消毒程序，如微波照射、次氯酸钠溶液、中性肥皂和市售抗菌溶液，应用于模拟实际使用寿命一年的时间。通过在不同深度进行拉伸和微压痕试验来研究机械性能。通过拉伸曲线拟合数学模型。拉伸参数（最大应力、最大应变、弹性和粘弹性参数）的变化进行了双因素方差分析和 Tukey 事后检验（α=0.05）。
大多数拉伸参数在不同的消毒程序和颌面材料之间存在显著差异，且材料变得更硬。微波照射对 PDMS 和 CPE 弹性体的影响最大，而商用抗菌溶液和中性肥皂则没有明显影响。微压痕和拉伸试验揭示了材料弹性模量和硬度的相似变化，而观察到的变化在较小深度更为明显。
PDMS 和 CPE 弹性体的拉伸和微压痕性能在经过四种不同程序消毒后发生了变化。两种材料的表面变化比材料内部更为剧烈。微波照射对两种弹性体的影响最大，因此根据本研究的结果，不建议对所检查的 PDMS 和 CPE 弹性体进行消毒。此外，微波照射和次氯酸钠溶液导致 CPE 样品表面（3μm）的变化更大，这一点可以通过微压痕结果得到证实。PDMS 受商用抗菌剂的影响较小，而 CPE 受中性肥皂的影响较小，这似乎是最适合的消毒技术。
