Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado, Denver, CO, USA.
J Pediatr Gastroenterol Nutr. 2013 Sep;57(3):401-12. doi: 10.1097/MPG.0b013e3182a025ee.
Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract that includes both Crohn disease (CD) and ulcerative colitis. Abdominal pain, rectal bleeding, diarrhea, and weight loss characterize both CD and ulcerative colitis. The incidence of IBD in the United States is 70 to 150 cases per 100,000 individuals and, as with other autoimmune diseases, is on the rise. CD can affect any part of the gastrointestinal tract from the mouth to the anus and frequently will include perianal disease. The first description connecting regional enteritis with perianal disease was by Bissell et al in 1934, and since that time perianal disease has become a recognized entity and an important consideration in the diagnosis and treatment of CD. Perianal Crohn disease (PCD) is defined as inflammation at or near the anus, including tags, fissures, fistulae, abscesses, or stenosis. The symptoms of PCD include pain, itching, bleeding, purulent discharge, and incontinence of stool. In this report, we review and discuss the etiology, diagnosis, evaluation, and treatment of PCD.
炎症性肠病是一种慢性胃肠道炎症性疾病，包括克罗恩病（CD）和溃疡性结肠炎。腹痛、直肠出血、腹泻和体重减轻是 CD 和溃疡性结肠炎的特征。在美国，IBD 的发病率为每 10 万人中有 70 至 150 例，与其他自身免疫性疾病一样，其发病率呈上升趋势。CD 可影响从口腔到肛门的胃肠道的任何部位，并且经常会包括肛周疾病。Bissell 等人于 1934 年首次将区域性肠炎与肛周疾病联系起来，从那时起，肛周疾病已成为 CD 诊断和治疗中的一个公认实体和重要考虑因素。肛周克罗恩病（PCD）定义为肛门或附近的炎症，包括皮赘、肛裂、瘘管、脓肿或狭窄。PCD 的症状包括疼痛、瘙痒、出血、脓性分泌物和粪便失禁。在本报告中，我们回顾和讨论了 PCD 的病因、诊断、评估和治疗。
