Daniel C, Choquet R
INSERM UMRS 872 équipe 20, CCS Patient - Assistance Publique - Hôpitaux de Paris, 05 rue Santerre - 75 012 Paris. E-mail:
Yearb Med Inform. 2013;8:185-9.
To summarize advances of excellent current research in the new emerging field of Clinical Research Informatics.
Synopsis of four key articles selected for the IMIA Yearbook 2013. The selection was performed by querying PubMed and Web of Science with predefined keywords. From the original set of 590 papers, a first subset of 461 articles which was in the scope of Clinical Research Informatics was refined into a second subset of 79 relevant articles from which 15 articles were retained for peer-review.
The four selected articles exemplify current research efforts conducted in the areas of data representation and management in clinical trials, secondary use of EHR data for clinical research, information technology platforms for translational and comparative effectiveness research and implementation of privacy control.
The selected articles not only illustrate how innovative information technology supports classically organized randomized controlled trials but also demonstrate that the long promised benefits of electronic health care data for research are becoming a reality through concrete platforms and projects.
总结临床研究信息学这一新兴领域当前优秀研究的进展。
对入选《IMIA 年鉴2013》的四篇关键文章进行概述。通过使用预定义关键词在PubMed和科学网中进行检索来进行文章选择。从最初的590篇论文中，将属于临床研究信息学范围内的461篇文章的第一个子集细化为79篇相关文章的第二个子集，从中保留15篇文章进行同行评审。
所选的四篇文章例证了当前在临床试验数据表示和管理、电子健康记录（EHR）数据用于临床研究的二次利用、转化和比较效果研究的信息技术平台以及隐私控制实施等领域所开展的研究工作。
所选文章不仅说明了创新信息技术如何支持传统组织的随机对照试验，还表明通过具体的平台和项目，长期以来所承诺的电子医疗保健数据用于研究的益处正成为现实。
