Department of Dermatology, Venereology and Leprology, Katuri Medical College, Guntur, Andhra Pradesh, India.
Indian J Dermatol Venereol Leprol. 2013 Sep-Oct;79(5):563-75. doi: 10.4103/0378-6323.116725.
Alopecia areata (AA) is a common form of non-scarring hair loss of scalp and/or body. Genetic predisposition, autoimmunity, and environmental factors play a major role in the etiopathogenesis of AA. Patchy AA is the most common form. Atopy and autoimmune thyroiditis are most common associated conditions. Peribulbar and intrabulbar lymphocytic inflammatory infiltrate resembling "swarm of bees" is characteristic on histopathology. Treatment is mainly focused to contain the disease activity. Corticosteroids are the preferred treatments in form of topical, intralesional, or systemic therapy. Camouflage in the form of wigs may be an alternative option in refractory cases.
斑秃(AA)是一种常见的非瘢痕性头皮和/或身体毛发脱落形式。遗传易感性、自身免疫和环境因素在 AA 的发病机制中起主要作用。斑片状 AA 是最常见的形式。特应性皮炎和自身免疫性甲状腺炎是最常见的相关疾病。球周和球内淋巴细胞炎症浸润类似于“蜂群”,这在组织病理学上具有特征性。治疗主要集中在控制疾病活动上。皮质类固醇是首选的治疗方法,包括局部、病灶内或全身治疗。在难治性病例中,假发等伪装可能是一种替代选择。