Department of Nutrition Sciences, College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania 19102, USA.
Curr Opin Endocrinol Diabetes Obes. 2013 Oct;20(5):396-400. doi: 10.1097/01.med.0000433064.78799.0c.
To provide an overview of the current advances in childhood obesity physiology, intervention, and prevention.
Structural and functional brain impairments are present in obese adolescents with metabolic syndrome (MetS). Aerobic training for 20 or 40 min per day produced similar affects on metabolic risk factors. Vitamin D supplementation has been shown to improve the metabolic risk factors in obese children; however, obese children require greater doses to treat vitamin D deficiency. A 10-week community-based exergaming weight management program significantly decreased the BMI in obese children.
There is surmounting research on MetS and its associated risk factors in obese children. Gaining a comprehensive overview of the factors associated with obesity in children is crucial in developing the most effective intervention strategies. Community-based and family-centered interventions have generated positive results in reducing children's BMI and improving MetS risk factors. In addition to obesity intervention efforts, ongoing prevention initiatives are imperative to reduce the prevalence of childhood obesity.
提供儿童肥胖生理学、干预和预防方面的最新进展概述。
患有代谢综合征（MetS）的肥胖青少年存在结构和功能脑损伤。每天进行 20 或 40 分钟的有氧运动对代谢危险因素有相似的影响。维生素 D 补充已被证明可改善肥胖儿童的代谢危险因素；然而，肥胖儿童需要更大剂量来治疗维生素 D 缺乏症。为期 10 周的基于社区的健身游戏体重管理计划可显著降低肥胖儿童的 BMI。
关于肥胖儿童代谢综合征及其相关危险因素的研究越来越多。全面了解与肥胖相关的因素对于制定最有效的干预策略至关重要。基于社区和以家庭为中心的干预措施已取得积极成果，可降低儿童的 BMI 并改善 MetS 风险因素。除了肥胖干预工作外，还必须开展持续的预防举措，以降低儿童肥胖症的流行率。
