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慢性腿部溃疡患者的疼痛程度、健康状况和伤口状况的关联。

Association of pain level, health and wound status in patients with chronic leg ulcers.

机构信息

Hautklinik Erlangen, Universitätsklinikum Erlangen, Ulmenweg 18, DE-91054 Erlangen, Germany.

出版信息

Acta Derm Venereol. 2014 Jan;94(1):50-3. doi: 10.2340/00015555-1635.

DOI:10.2340/00015555-1635
PMID:23975009
Abstract

Pain is a ubiquitous problem in patients with chronic leg wounds. The pain may be caused by the underlying pathology of the leg ulceration, the wound, wound treatment, or complications such as skin irritation around the ulcer. The objectives of this research were to evaluate the level of suffering endured by patients because of their ulcer-related pain, and to evaluate whether and how this pain is treated. In addition, to determine whether this pain influences quality of life and health status. In 2010, data were collected in order to characterize the patients by socio-demographic facts, such as age, gender, co-morbidity, pathogenesis of the wound, wound status of new patients, wound pain, and use of analgesics. In addition, modified EQ-5D questionnaires were distributed with additional questions concerning pain experience, treatment, and general health status. Of 103 patients, 45 were male and 58 female. Mean age was 67.8 years (males 65 years, females 70 years). Up to 69% had leg ulcerations due to vascular disease. Out of the 103 distributed questionnaires, 49 were returned and evaluated. Analysis showed that 82% of these patients reported wound-related pain, and 42% estimated their analgesics as not sufficiently pain relieving (mean value of the visual analogue scale (VAS) 4.9). Mean health status was 50.5 (maximal health status 100). Patients with a pain value ≥ 5 showed a lesser mean health status (42.2) than patients with a pain value < 5 (60.3). The proportion of patients receiving no, or only weak, analgesics was nearly the same for patients with VAS ≥ 5 and with VAS < 5. Further research in pain therapy is of utmost importance to improve the quality of life of patients with chronic wounds.

摘要

疼痛是患有慢性腿部伤口的患者普遍存在的问题。疼痛可能是由腿部溃疡、伤口、伤口处理或皮肤刺激等并发症的潜在病理引起的。本研究的目的是评估患者因溃疡相关疼痛而承受的痛苦程度,并评估这种疼痛是否以及如何得到治疗。此外,还要确定这种疼痛是否会影响生活质量和健康状况。2010 年,收集了数据以描述患者的社会人口统计学特征,如年龄、性别、合并症、伤口发病机制、新患者的伤口状况、伤口疼痛和镇痛药的使用。此外,还发放了经过修改的 EQ-5D 问卷,并附有关于疼痛体验、治疗和一般健康状况的额外问题。在 103 名患者中,45 名是男性,58 名是女性。平均年龄为 67.8 岁(男性 65 岁,女性 70 岁)。高达 69%的患者腿部溃疡是由血管疾病引起的。在发放的 103 份问卷中,有 49 份被回收并进行了评估。分析表明,82%的患者报告有伤口相关疼痛,42%的患者认为他们的镇痛药不能充分缓解疼痛(视觉模拟量表(VAS)的平均值为 4.9)。平均健康状况为 50.5(最大健康状况为 100)。疼痛值≥5 的患者的平均健康状况(42.2)低于疼痛值<5 的患者(60.3)。VAS≥5 和 VAS<5 的患者接受无或弱镇痛剂的比例几乎相同。进一步的疼痛治疗研究对于提高慢性伤口患者的生活质量至关重要。

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Int Wound J. 2022 Oct;19(6):1357-1369. doi: 10.1111/iwj.13730. Epub 2021 Dec 13.
2
Long-term Mortality among Patients with Chronic Ulcers.慢性溃疡患者的长期死亡率
Acta Derm Venereol. 2021 May 19;101(5):adv00455. doi: 10.2340/00015555-3803.
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Pain in persons with chronic venous leg ulcers: A systematic review and meta-analysis.慢性静脉性腿部溃疡患者的疼痛:系统评价和荟萃分析。
Int Wound J. 2020 Apr;17(2):466-484. doi: 10.1111/iwj.13296. Epub 2020 Jan 3.
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Rapid research and implementation priority setting for wound care uncertainties.快速研究和实施伤口护理不确定性的优先级设置。
PLoS One. 2017 Dec 5;12(12):e0188958. doi: 10.1371/journal.pone.0188958. eCollection 2017.
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Biomed Res Int. 2014;2014:819525. doi: 10.1155/2014/819525. Epub 2014 Apr 15.