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迟发性小脑共济失调:恶性疟原虫疟疾一种罕见的自限性并发症。

Delayed cerebellar ataxia: A rare self limiting complication of plasmodium falciparum malaria.

作者信息

Sakaria Amit K, Mahajan Sanket K, Desai Rajaram R, Shah Kuldeep B

机构信息

Department of Medicine, Krishna Institute of Medical Sciences University, Satara, Maharashtra, India.

出版信息

Adv Biomed Res. 2013 Mar 6;2:27. doi: 10.4103/2277-9175.107997. eCollection 2013.

Abstract

The classic presentation of malaria with paroxysms of fever is seen only in 50-70% of the patients. The development of immunity, the increasing resistance to anti-malarial drugs, and the indiscriminate use of anti-malarial drugs have led to malaria with the presentation of unusual features. Cerebellar ataxia, extrapyramidal rigidity and various psychiatric symptoms have been described either as early manifestations of cerebral malaria or as a part of post malaria neurological syndrome. In this case report, we will discuss one such patient of falciparum malaria infection who developed midline cerebellar signs, and responded to anti-malarial treatment.

摘要

仅有50%-70%的患者会出现疟疾典型的发热发作症状。免疫力的发展、对抗疟药物耐药性的增加以及抗疟药物的滥用导致疟疾出现了不寻常的特征。小脑共济失调、锥体外系强直和各种精神症状已被描述为脑型疟疾的早期表现或疟疾后神经综合征的一部分。在本病例报告中,我们将讨论一名感染恶性疟原虫的患者,该患者出现了中线小脑体征,并对抗疟治疗有反应。

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