Tayari Nazila, Ahrar Mohamad Hossein, Jafarpishe Mohamad Saleh
Department of Radiology, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2013 Mar 30;2:34. doi: 10.4103/2277-9175.109719. eCollection 2013.
Thalassemia is a hematologic disorder that causes ineffective hematopoiesis and is related to severe anemia, iron overload, extramedullary hematopoiesis, and hepatomegaly. Hepatomegaly is related to significant extramedullary hematopoiesis. The other sites that are involved in extramedullary hematopoiesis are spleen, lymph nodes, paraspinal regions, kidney, pleura, and intestine, but intracranial involvement is a rare presentation. We discuss about a case with intracranial medullary hematopoiesis in a thalassemic patient.
地中海贫血是一种血液系统疾病,可导致无效造血,并与严重贫血、铁过载、髓外造血和肝肿大有关。肝肿大与显著的髓外造血有关。参与髓外造血的其他部位是脾脏、淋巴结、脊柱旁区域、肾脏、胸膜和肠道,但颅内受累是一种罕见的表现。我们讨论了一例地中海贫血患者颅内髓性造血的病例。