Tabesh Homayoun, Shekarchizadeh Ahmad, Mahzouni Parvin, Mokhtari Mojgan, Abrishamkar Saeid, Abbasi Fard Salman
Department of Neurosurgery, Al-Zahra Hospital, Isfahan University Of Medical Sciences, Isfahan, Iran.
J Med Case Rep. 2011 Dec 19;5:580. doi: 10.1186/1752-1947-5-580.
Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia.
We present an unusual case of an intracranial extramedullary hematopoiesis with a choroid plexus origin in a 34-year-old Caucasian man with beta thalassemia intermedia, who presented with the complaints of chronic headache and rapid progressive visual loss.
An intracranial extramedullary hematopoiesis, although extremely rare, should be considered as a potential ancillary diagnosis in any thalassemic patient and therefore appropriate studies should be performed to investigate the probable intracranial ectopic marrow before any surgical intervention.
髓外造血发生于约15%的地中海贫血病例中。颅内髓外造血沉积是中重度地中海贫血中极为罕见的一种代偿过程。
我们报告一例不寻常的颅内髓外造血病例，起源于脉络丛，患者为一名34岁患有中间型β地中海贫血的白种男性，主诉慢性头痛和视力快速进行性丧失。
颅内髓外造血虽然极为罕见，但在任何地中海贫血患者中都应被视为一种潜在的辅助诊断，因此在任何手术干预之前，都应进行适当的研究以调查可能的颅内异位骨髓。
