Gazi University, Faculty of Pharmacy, Department of Pharmacognosy, Etiler 06330, Ankara,Turkey.
Curr Drug Targets. 2013 Dec;14(13):1611-8. doi: 10.2174/13894501113149990205.
Osteoporosis causes bone loss, and makes bone to susceptible to fracture. The main cause of osteoporosis is estrogen deficiency. Estrogen, calcitonin, calcium, vitamin D and antioxidants can be used to prevent osteoporosis. For the treatment of osteoporosis, the potential biological activities of traditional medicines have been subjected to scientific evaluation, since synthetic drugs are considered to have several side effects and they lack efficacy. Therefore, more extensive research should be carried out to investigate the medicinal plants to be used as an alternative treatment for osteoporosis. The present review focuses on the scientific researches on the assessment of anti-osteoporotic activity of medicinal plants.
骨质疏松症导致骨质流失,使骨骼易骨折。骨质疏松症的主要原因是雌激素缺乏。雌激素、降钙素、钙、维生素 D 和抗氧化剂可用于预防骨质疏松症。对于骨质疏松症的治疗,传统药物的潜在生物活性已经过科学评估,因为合成药物被认为有几种副作用,而且疗效不佳。因此,应该进行更广泛的研究,以调查药用植物,将其用作骨质疏松症的替代治疗方法。本文综述重点介绍了药用植物抗骨质疏松活性评估的科学研究。