Kaltoft Britta, Løvgren Preben, Frølund Ulf, Welinder Jakob
Øre-, næse- og halskirurgisk Afdeling, Køge Sygehus, Lykkebækvej 1-3, 4600 Køge.
Ugeskr Laeger. 2013 Aug 26;175(35):1966-8.
Primary localized amyloidosis (PLA) is a rare benign disease defined by the presence of extracellular deposits of insoluble amyloid fibrils without systemic involvement. We report a case story of a patient with a tumour in pharynx. It was excised and based on histopathology the diagnosis PLA was confirmed. The patient was examined for systemic amyloidosis (SA). All tests were normal except for an elevated lactate dehydrogenase level. Using PET/CT we found a hypermetabolic lymph node, but the ultrasound examination was normal. The patient continued follow-up and has so far no sign of recurrence of SA.
原发性局限性淀粉样变性（PLA）是一种罕见的良性疾病，其定义为存在不溶性淀粉样纤维的细胞外沉积物且无全身受累。我们报告一例咽部肿瘤患者的病例。肿瘤被切除，基于组织病理学确诊为PLA。对该患者进行了全身淀粉样变性（SA）检查。除乳酸脱氢酶水平升高外，所有检查均正常。使用PET/CT我们发现一个代谢亢进的淋巴结，但超声检查正常。该患者继续接受随访，迄今为止尚无SA复发的迹象。
