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扁桃体切除术后的严重并发症:它们实际有多常见?

Serious complications following tonsillectomy: how frequent are they really?

作者信息

Windfuhr Jochen P

机构信息

Department of Otorhinolaryngology, Plastic Head and Neck Surgery, Kliniken Maria Hilf, Mönchengladbach, Germany.

出版信息

ORL J Otorhinolaryngol Relat Spec. 2013;75(3):166-73. doi: 10.1159/000342317. Epub 2013 Aug 22.

Abstract

INTRODUCTION

Quality assurance in health care involves the evaluation of outcomes, cost-benefit ratios, and access to the delivery system. This literature review was undertaken to clarify the incidence of serious posttonsillectomy complications to better understand the outcome component of quality assurance.

MATERIAL AND METHODS

A Medline review was undertaken using the key word 'tonsillectomy' AND each of the following: 'serious', 'complications' and 'review'; 'meta-analysis', 'Cochrane'; 'life-threatening', 'death' and 'disability'.

RESULTS

454 articles were identified with the following search items in combination with 'tonsillectomy': 'serious' (154), 'complications', 'review' (24), 'meta-analysis' (38), 'Cochrane' (43), 'life-threatening' (87), 'death' (91), 'disability' (17). Sixty-seven articles described a complication rate and were therefore eligible for review: 22 case reports, 9 case series, 2 questionnaires and 33 studies with a more or less precise complication rate were obtainable. Most articles (n = 30) reported the rate of posttonsillectomy hemorrhage with a considerable range. Fifteen articles reported the incidence of death, which ranged from 1:7,132 to 1:170,000 and almost always resulted from excessive hemorrhage. All other complications were mentioned in case reports.

CONCLUSION

The most common postoperative complication of tonsillectomy is bleeding. However, the incidence varies considerably across studies depending on the study design, follow-up and definition of postoperative bleeding. Other serious adverse events, such as neurological disabilities, emphysema (with or without pneumomediastinum), or vascular problems outside the neck are infrequent.

摘要

引言

医疗保健中的质量保证涉及对结果、成本效益比以及医疗服务提供系统的可及性进行评估。进行此次文献综述是为了明确扁桃体切除术后严重并发症的发生率,以便更好地理解质量保证中的结果部分。

材料与方法

使用关键词“扁桃体切除术”以及以下各词进行医学文献数据库检索:“严重的”“并发症”“综述”;“荟萃分析”“考克兰系统评价”;“危及生命的”“死亡”“残疾”。

结果

通过将以下检索词与“扁桃体切除术”组合,共识别出454篇文章:“严重的”(154篇)、“并发症”“综述”(24篇)、“荟萃分析”(38篇)、“考克兰系统评价”(43篇)、“危及生命的”(87篇)、“死亡”(91篇)、“残疾”(17篇)。67篇文章描述了并发症发生率,因此符合综述条件:22篇病例报告、9篇病例系列、2份调查问卷以及33项或多或少有精确并发症发生率的研究可供获取。大多数文章(n = 30)报告了扁桃体切除术后出血率,范围差异很大。15篇文章报告了死亡率,范围从1:7,132至1:170,000,几乎均由大出血导致。所有其他并发症在病例报告中提及。

结论

扁桃体切除术后最常见的并发症是出血。然而,根据研究设计、随访情况以及术后出血的定义,不同研究中的发生率差异很大。其他严重不良事件,如神经功能障碍、肺气肿(伴或不伴纵隔气肿)或颈部以外的血管问题则较为罕见。

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