Department of Otolaryngology-Head and Neck Surgery, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Department of Otolaryngology-Head and Neck Surgery, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241263851. doi: 10.1177/19160216241263851.
Adenotonsillectomy is one of the most common surgical procedures worldwide. The current standard for securing the airway in patients undergoing adenotonsillectomy is endotracheal tube (ETT) intubation. Several studies have investigated the use of the laryngeal mask airway (LMA) in this procedure. We conducted a systematic review and meta-analysis to compare the safety and efficacy of the LMA versus ETT in adenotonsillectomy.
Databases were searched from inception to 2022 for randomized controlled trials and comparative studies. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. The primary outcome is the rate of perioperative respiratory adverse events (PRAEs). Secondary outcomes included the rate of conversion to ETT, desaturations, nausea/vomiting, and surgical time. A subgroup analysis, risk of bias, publication bias, and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) assessments were also performed.
Twelve studies were included in the analysis (4176 patients). The mean overall conversion to ETT was 8.36% [95% confidence interval (CI) = 8.17, 8.54], and for the pediatric group 8.27% (95% CI = 8.08, 8.47). The mean rate of conversion to ETT secondary to complications was 2.89% (95% CI = 2.76, 3.03) while the rest was from poor surgical access. Overall, there was no significant difference in PRAEs [odds ratio (OR) 1.16, 95% CI = 0.60, 2.22], desaturations (OR 0.79, 95% CI = 0.38, 1.64), or minor complications (OR 0.89, 95% CI = 0.50, 1.55). The use of LMA yielded significantly shorter operative time (mean difference -4.38 minutes, 95% CI = -8.28, -0.49) and emergence time (mean difference -4.15 minutes, 95% CI = -5.63, -2.67).
For adenotonsillectomy surgery, LMA is a safe alternative to ETT and requires less operative time. Careful patient selection and judgment of the surgeon and anesthesiologist are necessary, especially given the 8% conversion to ETT rate.
腺样体切除术是全球最常见的手术之一。目前,在接受腺样体切除术的患者中,确保气道安全的标准是气管内插管(ETT)。有几项研究调查了在该手术中使用喉罩气道(LMA)的情况。我们进行了一项系统评价和荟萃分析,以比较 LMA 与 ETT 在腺样体切除术中的安全性和疗效。
从成立到 2022 年,我们在数据库中搜索了随机对照试验和比较研究。遵循了系统评价和荟萃分析的首选报告项目(PRISMA)指南。主要结局是围手术期呼吸不良事件(PRAE)的发生率。次要结局包括转换为 ETT、饱和度降低、恶心/呕吐和手术时间。还进行了亚组分析、偏倚风险、发表偏倚和推荐评估、制定与评估(GRADE)评估。
共有 12 项研究纳入分析(4176 例患者)。总体上,转换为 ETT 的平均发生率为 8.36%[95%置信区间(CI)=8.17,8.54],儿科组为 8.27%(95%CI=8.08,8.47)。因并发症而转换为 ETT 的平均发生率为 2.89%(95%CI=2.76,3.03),其余原因是手术入路不佳。总体而言,PRAE[比值比(OR)1.16,95%CI=0.60,2.22]、饱和度降低(OR 0.79,95%CI=0.38,1.64)或轻微并发症(OR 0.89,95%CI=0.50,1.55)无显著差异。使用 LMA 可显著缩短手术时间(平均差值-4.38 分钟,95%CI=-8.28,-0.49)和苏醒时间(平均差值-4.15 分钟,95%CI=-5.63,-2.67)。
对于腺样体切除术,LMA 是 ETT 的安全替代方法,并且需要更少的手术时间。需要仔细选择患者,并由外科医生和麻醉师进行判断,特别是考虑到 8%的 ETT 转换率。