Müller-Wiefel A-S, Reifenberger J, Bruch-Gerharz D, Helbig D
Hautklinik und Hauttumorzentrum, Universitätsklinikum Düsseldorf, Düsseldorf, Deutschland.
Hautarzt. 2013 Oct;64(10):722-4. doi: 10.1007/s00105-013-2641-y.
Syphilis is a sexually transmitted disease caused by Treponema pallidum which evolves through three overlapping stages. A 50-year-old woman presented with an expanding painless granulomatous nodule on her lower lip in combination with a maculo-papular exanthem. Both serologic studies and microscopic examination indicated an infection with Treponema pallidum. This case shows an unusual granulomatous nodular presentation of syphilis on the lower lip, emphasizing the variable clinical and histological manifestations syphilis, which shows an increasing number of new infections worldwide in recent years.
梅毒是一种由梅毒螺旋体引起的性传播疾病，其病程分为三个重叠阶段。一名50岁女性下唇出现一个不断扩大的无痛性肉芽肿性结节，并伴有斑丘疹性皮疹。血清学检查和显微镜检查均表明感染了梅毒螺旋体。该病例显示了梅毒在下唇出现不寻常的肉芽肿性结节表现，强调了梅毒临床表现和组织学表现的多样性，近年来全球新感染病例数呈上升趋势。
