Mörkl S, Painold A, Kapfhammer H-P, Holl A K
Universitätsklinik für Psychiatrie, Medizinische Universität Graz, Auenbruggerplatz 31, 8036, Graz, Österreich.
Nervenarzt. 2014 Sep;85(9):1128-32. doi: 10.1007/s00115-013-3864-y.
Patients with major depression commonly report memory deficits but studies on this topic have shown inconsistent results. The aim of this study was to determine whether patients with major depression showed any differences in explicit verbal memory compared to healthy controls.
We used the California verbal learning test (CVLT) in order to compare the explicit verbal memory of 30 patients (21 women and 9 men) to a healthy control group (23 women and 10 men).
The results showed no significant differences between verbal memory performance of patients with major depression and healthy controls.
Verbal memory of depressive patients with antidepressant pharmacotherapy showed no significant differences compared to a healthy control group. It can be assumed that verbal memory in depression depends on variable parameters (e.g. age, severity and duration of depression and medication). More studies with a larger number of patients should be conducted to obtain reliable results about explicit verbal memory in depression.
重度抑郁症患者通常报告存在记忆缺陷，但关于这一主题的研究结果并不一致。本研究的目的是确定重度抑郁症患者与健康对照组相比，在显性言语记忆方面是否存在差异。
我们使用加利福尼亚言语学习测验（CVLT），以比较30例患者（21名女性和9名男性）与健康对照组（23名女性和10名男性）的显性言语记忆。
结果显示，重度抑郁症患者与健康对照组在言语记忆表现上无显著差异。
接受抗抑郁药物治疗的抑郁症患者的言语记忆与健康对照组相比无显著差异。可以推测，抑郁症中的言语记忆取决于多种可变参数（如年龄、抑郁症的严重程度和持续时间以及药物治疗）。应该进行更多纳入更多患者的研究，以获得关于抑郁症中显性言语记忆的可靠结果。
