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工作相关风险因素与大样本工作人群中外侧肱骨上髁炎的发病关系。

Work-related risk factors for incidence of lateral epicondylitis in a large working population.

机构信息

Inserm U1018, UVSQ, Unité de pathologie professionnelle U1018, CHU Poincaré, 104 bd Poincaré, 92380 Garches, France.

出版信息

Scand J Work Environ Health. 2013 Nov;39(6):578-88. doi: 10.5271/sjweh.3380. Epub 2013 Aug 26.

Abstract

OBJECTIVES

This study aims to estimate the association between repeated measures of occupational risk factors and the incidence of lateral epicondylitis in a large working population.

METHODS

A total of 3710 workers in a French region were included in 2002-2005, and among them 1046 had a complete follow-up in 2007-2010. At both stages, occupational health physicians assessed the presence of lateral epicondylitis and workers self-reported their occupational exposures. Poisson models were performed to assess the incidence rate ratios (IRR) separately by sex using multiple imputed data.

RESULTS

The annual incidence rate of lateral epicondylitis was estimated as 1.0 [95% confidence interval (95% CI) 0.7-1.3] per 100 workers among men and 0.9 (95% CI 0.6-1.3) among women. Workers aged >45 years had higher incidence than those aged <30 years (significant at 10%). Among men, high physical exertion combined with elbow flexion/extension or extreme wrist bending (>2 hours/day) was a risk factor, with an age-adjusted IRR of 3.2 (95% CI 1.5-6.4) for workers exposed at both questionnaires [3.3 (95% CI 1.4-7.6) among women].

CONCLUSIONS

This study highlights the importance of temporal dimensions for occupational risk factors on the incidence of lateral epicondylitis. Further research should evaluate the risk associated with the duration and repetition of occupational exposure on the incidence of lateral epicondylitis.

摘要

目的

本研究旨在评估职业危险因素的重复测量与大量工作人群中外侧髁炎发病的关系。

方法

2002-2005 年,法国某地区共纳入 3710 名工人,其中 1046 名工人在 2007-2010 年完成了完整随访。在两个阶段,职业健康医生评估外侧髁炎的存在,工人自我报告职业暴露情况。使用多重插补数据,使用泊松模型分别按性别评估发病率比值比(IRR)。

结果

男性外侧髁炎的年发病率估计为 1.0 [95%置信区间(95%CI)0.7-1.3]/100 名工人,女性为 0.9(95%CI 0.6-1.3)。年龄>45 岁的工人发病率高于年龄<30 岁的工人(10%显著)。男性中,高体力劳动结合肘部屈伸或极端手腕弯曲(>2 小时/天)是一个危险因素,两个问卷均暴露的工人年龄调整的 IRR 为 3.2(95%CI 1.5-6.4)[女性为 3.3(95%CI 1.4-7.6)]。

结论

本研究强调了职业危险因素对外侧髁炎发病的时间维度的重要性。进一步的研究应该评估职业暴露的持续时间和重复对外侧髁炎发病的风险。

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