Nadeau Christine, Kuperstein Arthur S, Mupparapu Muralidhar, Stoopler Eric T
Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.
Spec Care Dentist. 2013 Sep-Oct;33(5):255-9. doi: 10.1111/scd.12029. Epub 2013 May 14.
Pseudoxanthoma elasticum (PXE) is a disorder characterized by progressive degeneration of elastic fibers and ectopic mineralization. Cutaneous manifestations are a hallmark of this disease and organs that may be affected by the disease process include cardiovascular, central nervous system, ocular and gastrointestinal systems. Oral manifestations of PXE have been previously reported as intramucosal nodules observed on various intraoral surfaces. We present a case of a 46-year-old female with PXE diagnosed with temporomandibular disorder (TMD). To our knowledge, this is the first report of a patient with TMD coexisting with PXE in the scientific literature.
弹性假黄瘤（PXE）是一种以弹性纤维进行性退变和异位矿化为特征的疾病。皮肤表现是该疾病的标志，可能受疾病进程影响的器官包括心血管系统、中枢神经系统、眼部和胃肠道系统。PXE的口腔表现此前曾报道为在各种口腔内表面观察到的黏膜内结节。我们报告一例46岁患有PXE的女性被诊断为颞下颌关节紊乱病（TMD）。据我们所知，这是科学文献中首例TMD与PXE共存患者的报告。
