The Key Laboratory of Bioorganic Phosphorous Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
Org Lett. 2013 Sep 6;15(17):4414-7. doi: 10.1021/ol401959d. Epub 2013 Aug 27.
Efficient synthesis of tetraoxacalix[2]perfluoroarene[2]triazines and their isomeric analogs from a one-pot macrocyclic condensation reaction of methoxy- and amino-substituted dichlorotriazines with tetrafluorobenzene-1,3-, -1,4-, and -1,2-diols was developed. X-ray analysis demonstrates that they adopt drastically different 1,3-alternate conformations in the crystalline state while in solution they undergo very fast conformational changes relative to the NMR time scale.
从甲氧基和氨基取代的二氯三嗪与四氟苯-1,3-, -1,4-和-1,2-二醇的一锅法大环缩合反应中，高效合成了四氧杂杯[2]全氟芳烃[2]三嗪及其异构类似物。X 射线分析表明，它们在晶体状态下采用完全不同的 1,3-交替构象，而在溶液中它们相对于 NMR 时间尺度发生非常快速的构象变化。
