Rusconi Maria Luisa, Carelli Laura, Stampatori Chiara, Mattioli Flavia
a Department of Human and Social Sciences , University of Bergamo , Bergamo , Italy.
Neurocase. 2014;20(5):501-9. doi: 10.1080/13554794.2013.826682. Epub 2013 Aug 27.
We describe behavioral and neuropsychological outcome of a patient (N.S.), who showed a bilateral paramedian thalamic ischemic lesion, with particular reference to the longitudinal evolution of topographical disorientation (TD) and confabulations. We report clinical neuropsychological/behavioral data over a 43-month follow-up. The results show early after the stroke a severe amnesic-confabulatory syndrome with dysexecutive deficits, associated with memory disorders both for visuo-spatial and verbal materials and TD both for known and new places. Behavioral disinhibition and anosognosia for cognitive deficits were also observed. All cognitive impairments have been recovered during the long-term follow-up. Bilateral paramedian thalamic infarcts often lead to severe and long-lasting neurological and cognitive impairments. Only a few cases showed good recovery. Our patient represents an interesting and uncommon case of bilateral paramedian thalamic syndrome with a significant neuropsychological recovery.
我们描述了一名患者（N.S.）的行为和神经心理学结果，该患者双侧丘脑旁正中出现缺血性病变，特别提及了地形定向障碍（TD）和虚构的纵向演变。我们报告了43个月随访期间的临床神经心理学/行为数据。结果显示，中风后早期出现严重的遗忘 - 虚构综合征，伴有执行功能障碍，与视觉空间和言语材料的记忆障碍以及新旧地点的TD相关。还观察到行为抑制解除和对认知缺陷的疾病感缺失。在长期随访中，所有认知障碍均已恢复。双侧丘脑旁正中梗死常导致严重且持久的神经和认知障碍。只有少数病例显示恢复良好。我们的患者代表了双侧丘脑旁正中综合征的一个有趣且罕见的病例，具有显著的神经心理学恢复。
