Lin Guoliang, Zhang Xiong, Hu Beilei, Zou Ming, Chen Songfang, Gong Yuqiang, Cheng Bihuan, He Zhiyong
Department of Critical Care Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Eur Neurol. 2017;77(3-4):197-200. doi: 10.1159/000458705. Epub 2017 Feb 11.
The study aimed to evaluate the clinical features in patients with bilateral and unilateral paramedian thalamic infarcts.
Twenty-one patients with paramedian thalamic infarcts were included, and their case records were reviewed. We focused on the patients' neuroimaging and neurological symptoms including the duration of coma, vertical gaze palsy, and memory impairment. The causes of bilateral and unilateral paramedian thalamic infarcts were also investigated.
Nine patients had bilateral paramedian thalamic infarcts and 12 patients had unilateral lesions. As an initial symptom, coma had occurred in 5 patients with bilateral lesions and 4 patients with unilateral lesions. Bilateral vertical gaze palsy and memory impairment were found in both groups. Most of them recovered well, except 1 patient who died due to bilateral thalamic paramedian infarction.
Our results show that both bilateral and unilateral paramedian thalamic infarcts can cause coma, vertical gaze palsy, and memory impairment. This may promote our understanding of paramedian thalamic infarction.
本研究旨在评估双侧和单侧丘脑旁正中梗死患者的临床特征。
纳入21例丘脑旁正中梗死患者,并回顾其病例记录。我们重点关注患者的神经影像学和神经症状,包括昏迷持续时间、垂直凝视麻痹和记忆障碍。还对双侧和单侧丘脑旁正中梗死的病因进行了调查。
9例患者为双侧丘脑旁正中梗死,12例患者为单侧病变。作为初始症状,5例双侧病变患者和4例单侧病变患者出现了昏迷。两组均发现双侧垂直凝视麻痹和记忆障碍。除1例因双侧丘脑旁正中梗死死亡的患者外,大多数患者恢复良好。
我们的结果表明,双侧和单侧丘脑旁正中梗死均可导致昏迷、垂直凝视麻痹和记忆障碍。这可能有助于我们对丘脑旁正中梗死的理解。