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常染色体显性遗传性脊髓小脑共济失调患者跌倒风险更高,存在严重的平衡功能损害,且功能活动能力下降。

Patients with autosomal dominant spinocerebellar ataxia have more risk of falls, important balance impairment, and decreased ability to function.

作者信息

Aizawa Carolina Yuri P, Pedroso José Luiz, Braga-Neto Pedro, Callegari Marilia Rezende, Barsottini Orlando Graziani Povoas

机构信息

Universidade Federal de São Paulo, Department of Neurology, São Paulo, Brazil.

出版信息

Arq Neuropsiquiatr. 2013 Aug;71(8):508-11. doi: 10.1590/0004-282X20130094.

DOI:10.1590/0004-282X20130094
PMID:23982006
Abstract

OBJECTIVES

To assess balance and ability to function in patients with spinocerebellar ataxia.

METHODS

A total of 44 patients with different spinocerebellar ataxia types 1, 2, 3, and 6 were evaluated using the Tinetti balance and gait assessment and the functional independence measure. The scale for the assessment and rating of ataxia and the international cooperative ataxia rating scale were used to evaluate disease severity.

RESULTS

Most patients showed significant risk of falls. The balance scores were significantly different in spinocerebellar ataxia types. A significant positive correlation between balance and disease severity was found.

CONCLUSION

Patients with spinocerebellar ataxia have important balance impairment and risk of falls that influence the ability to function such as self-care, transfers, and locomotion. Furthermore, the more severe ataxia is, the more compromised are postural balance, risk of falls, and ability to function.

摘要

目的

评估脊髓小脑共济失调患者的平衡能力和功能。

方法

使用Tinetti平衡和步态评估以及功能独立性测量,对44例不同类型(1型、2型、3型和6型)脊髓小脑共济失调患者进行评估。采用共济失调评估与评分量表和国际合作共济失调评分量表评估疾病严重程度。

结果

大多数患者显示出明显的跌倒风险。脊髓小脑共济失调各类型之间的平衡得分存在显著差异。发现平衡与疾病严重程度之间存在显著正相关。

结论

脊髓小脑共济失调患者存在重要的平衡障碍和跌倒风险,这会影响诸如自我护理、转移和移动等功能。此外,共济失调越严重,姿势平衡、跌倒风险和功能能力受损就越严重。

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